显微注射转化型ras蛋白可诱导c-fos表达。
Microinjection of transforming ras protein induces c-fos expression.
作者信息
Stacey D W, Watson T, Kung H F, Curran T
出版信息
Mol Cell Biol. 1987 Jan;7(1):523-7. doi: 10.1128/mcb.7.1.523-527.1987.
Abstract
Microinjection of p21ras induced c-fos protein accumulation in three types of 3T3 cells. The induction was rapid and efficient and persisted for many hours. In addition, anti-ras antibody dramatically reduced c-fos accumulation after serum stimulation of injected cells. However, cells which expressed p21ras continuously did not maintain a high level of c-fos expression.
摘要
向三种3T3细胞中显微注射p21ras可诱导c-fos蛋白积累。这种诱导迅速且高效，并持续数小时。此外，抗ras抗体在血清刺激注射细胞后显著降低了c-fos的积累。然而，持续表达p21ras的细胞并未维持高水平的c-fos表达。
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