Arkowitz Robert A, Bassilana Martine
Université Côte d'Azur, CNRS, Inserm, Institute of Biology Valrose, Parc Valrose, Nice, France.
F1000Res. 2019 May 21;8. doi: 10.12688/f1000research.18546.1. eCollection 2019.
Morphological changes are critical for the virulence of a range of plant and human fungal pathogens. is a major human fungal pathogen whose ability to switch between different morphological states is associated with its adaptability and pathogenicity. In particular, can switch from an oval yeast form to a filamentous hyphal form, which is characteristic of filamentous fungi. What mechanisms underlie hyphal growth and how are they affected by environmental stimuli from the host or resident microbiota? These questions are the focus of intensive research, as understanding hyphal growth has broad implications for cell biological and medical research.
形态变化对于一系列植物和人类真菌病原体的毒力至关重要。是一种主要的人类真菌病原体，其在不同形态状态之间转换的能力与其适应性和致病性相关。特别是，它可以从椭圆形酵母形态转变为丝状菌丝形态，这是丝状真菌的特征。菌丝生长的潜在机制是什么，它们如何受到来自宿主或常驻微生物群的环境刺激的影响？这些问题是深入研究的重点，因为了解菌丝生长对细胞生物学和医学研究具有广泛的意义。
需注意，原文中部分关键信息缺失（文中有两个“ ”处），翻译可能会因信息不完整存在一定局限性。
