Centre of Research Excellence in Nutrition and Metabolism, Institute for Medical Research, University of Belgrade, studentskitry 1, Belgrade, Serbia.
Faculty of Medicine, University of Banja Luka, Bosnia and Herzegovina, Republika Srpska.
Curr Pharm Des. 2019;25(16):1817-1827. doi: 10.2174/1381612825666190708183941.
Pomegranate (Punica granatum L.) fruits are widely consumed and used as preventive and therapeutic agents since ancient times. Pomegranate is a rich source of a variety of phytochemicals, which are responsible for its strong antioxidative and anti-inflammatory potential.
The aim of this review is to provide an up-to-date overview of the current knowledge of chemical structure and potential health benefits of pomegranate.
A comprehensive search of available literature.
The review of the literature confirms that juice and extracts obtained from different parts of this plant, including fruit peel, seeds, and leaves exert health benefits in both in vitro and in vivo studies. The antidiabetic, antihypertensive, antimicrobial and anti-tumour effects of pomegranate fruit are of particular scientific and clinical interest.
Further investigations are required to clarify the mechanism of action of the bioactive ingredients and to reveal full potential of pomegranate as both preventive and therapeutic agent.
石榴(Punica granatum L.)果实自古以来就被广泛食用和用作预防和治疗药物。石榴是多种植物化学物质的丰富来源,这些物质是其强大抗氧化和抗炎潜力的原因。
本综述旨在提供石榴化学结构和潜在健康益处的最新概述。
对现有文献进行全面搜索。
对文献的综述证实,从这种植物的不同部位(包括果皮、种子和叶子)获得的果汁和提取物在体外和体内研究中都具有健康益处。石榴果实的降血糖、降血压、抗菌和抗肿瘤作用具有特别的科学和临床意义。
需要进一步的研究来阐明生物活性成分的作用机制,并揭示石榴作为预防和治疗药物的全部潜力。