Department of Prevention and Community Health, Milken Institute School of Public Health, The George Washington University, 950 New Hampshire Ave. NW, Washington, DC, 20052, USA.
Department of Epidemiology, Milken Institute School of Public Health, The George Washington University, Washington, DC, USA.
BMC Public Health. 2019 Jul 18;19(1):964. doi: 10.1186/s12889-019-7299-7.
Smoking during pregnancy has adverse health consequences for the mother and fetus. E-cigarettes could aid with smoking cessation but there is limited research on the prevalence and patterns of e-cigarette use, and their association with smoking cessation among pregnant smokers.
We conducted a secondary analysis of a randomized controlled trial of a text-messaging program for smoking cessation among a U.S. national cohort of pregnant smokers (n = 428). Outcomes assessed were trajectories of e-cigarettes use from baseline to one-month follow-up, and longitudinal association between e-cigarette use at baseline and smoking cessation at one-month follow-up.
At baseline, 74 (17.29%) pregnant smokers used e-cigarettes in the past 30 days and 36 (8.41%) used e-cigarettes in the past 7 days. The primary reason stated for using e-cigarettes during pregnancy was for quitting. E-cigarette use between baseline and 1-month was inconsistent. Of 36 dual-users at baseline, 20 (55.56%) stopped using e-cigarettes by the 1-month follow-up and 14 initiated e-cigarette use. There was no evidence of an association between e-cigarette use at baseline and the primary smoking cessation outcome, 7-day point prevalence abstinence [adjusted odds ratio = 0.79, 95% confidence intervals = 0.33-1.92].
A secondary analysis of a national sample of pregnant smokers indicates that use of e-cigarettes is inconsistent and is not associated with improved smoking cessation outcomes. There is an urgent need to further examine the risk and benefits of e-cigarette use, especially during pregnancy.
孕期吸烟会对母亲和胎儿的健康造成不良后果。电子烟可能有助于戒烟，但关于电子烟的使用频率和模式，以及它们与孕期吸烟女性戒烟的关系，研究有限。
我们对一项美国全国孕妇吸烟人群短信戒烟干预随机对照试验进行了二次分析（n=428）。评估的结局包括从基线到一个月随访的电子烟使用轨迹，以及基线时使用电子烟与一个月随访时戒烟之间的纵向关联。
在基线时，74 名（17.29%）孕妇在过去 30 天内使用过电子烟，36 名（8.41%）孕妇在过去 7 天内使用过电子烟。孕妇在孕期使用电子烟的主要原因是为了戒烟。基线到一个月期间电子烟使用情况不一致。在基线时的 36 名双重使用者中，20 名（55.56%）在一个月随访时停止使用电子烟，14 名开始使用电子烟。基线时使用电子烟与主要戒烟结局（7 天点预估值）之间无关联，调整后的比值比为 0.79（95%置信区间为 0.33-1.92）。
对全国孕妇吸烟样本的二次分析表明，电子烟的使用情况不一致，与戒烟效果改善无关。迫切需要进一步研究电子烟使用的风险和益处，特别是在孕期。
