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美国国家科学院-国家研究委员会双胞胎登记处与杜克大学衰老记忆双胞胎研究:最新进展

The NAS-NRC Twin Registry and Duke Twins Study of Memory in Aging: An Update.

作者信息

Gatz Margaret, Plassman Brenda L, Tanner Caroline M, Goldman Samuel M, Swan Gary E, Chanti-Ketterl Marianne, Walters Ellen E, Butler David A

机构信息

Center for Economic and Social Research, University of Southern California, Los Angeles, California, USA.

Department of Psychiatry & Behavioral Science, School of Medicine, Duke University, Durham, North Carolina, USA.

出版信息

Twin Res Hum Genet. 2019 Dec;22(6):757-760. doi: 10.1017/thg.2019.45. Epub 2019 Jul 29.

Abstract

The National Academy of Sciences-National Research Council (NAS-NRC) Twin Registry is one of the oldest, national population-based twin registries in the USA. It comprises 15,924 White male twin pairs born in the years 1917-1927 (N = 31.848), both of whom served in the armed forces, chiefly during World War II. This article updates activities in this registry since the most recent report in Twin Research and Human Genetics (Page, 2006). Records-based data include information from enlistment charts and Veterans Administration data linkages. There have been three major epidemiologic questionnaires and an education and earnings survey. Separate data collection efforts with the NAS-NRC registry include the National Heart, Lung, and Blood Institute (NHLBI) subsample, the Duke Twins Study of Memory in Aging and a clinically based study of Parkinson's disease. Progress has been made on consolidating the various data holdings of the NAS-NRC Twin Registry. Data that had been available through the National Academy of Sciences are now freely available through National Archive of Computerized Data on Aging (NACDA).

摘要

美国国家科学院 - 国家研究委员会(NAS - NRC)双胞胎登记处是美国最古老的、基于全国人口的双胞胎登记处之一。它包含1917年至1927年出生的15924对白人男性双胞胎(N = 31848),他们两人都曾在武装部队服役,主要是在第二次世界大战期间。本文更新了自《双胞胎研究与人类遗传学》(佩奇,2006年)上一次报告以来该登记处的活动情况。基于记录的数据包括入伍图表信息和退伍军人管理局的数据链接。已经进行了三项主要的流行病学问卷调查以及一项教育和收入调查。与NAS - NRC登记处单独开展的数据收集工作包括国立心肺血液研究所(NHLBI)的子样本、杜克大学衰老记忆双胞胎研究以及一项基于临床的帕金森病研究。在整合NAS - NRC双胞胎登记处的各种数据方面已经取得了进展。过去通过美国国家科学院获取的数据现在可通过国家老龄化计算机化数据档案库(NACDA)免费获取。

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