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重症肌无力患者的T淋巴细胞亚群

Subpopulations of T lymphocytes in myasthenia gravis patients.

作者信息

Piantelli M, Lauriola L, Carbone A, Evoli A, Tonali P, Musiani P

出版信息

Clin Exp Immunol. 1979 Apr;36(1):85-9.

Abstract

Subpopulations of human peripheral blood T lymphocytes were examined in twenty-three myasthenic patients. T lymphocytes bearing receptors for the Fc portion of IgG (T gamma) were significantly increased in a third of the patients examined. T lymphocytes bearing receptors for the Fc portion of IgM (Tmu) were within normal values in all but two patients. Possible implications of these cells in the pathogenesis of myasthenia gravis are discussed.

摘要

对23例重症肌无力患者的人外周血T淋巴细胞亚群进行了检测。在三分之一的受检患者中,带有IgG Fc段受体的T淋巴细胞(Tγ)显著增加。除两名患者外,带有IgM Fc段受体的T淋巴细胞(Tμ)均在正常范围内。讨论了这些细胞在重症肌无力发病机制中的可能意义。

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Myasthenia as an autoimmune disease: clinical aspects.重症肌无力作为一种自身免疫性疾病:临床方面
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The pathology of the thymus gland in myasthenia gravis.重症肌无力患者胸腺的病理学表现。
Ann N Y Acad Sci. 1966 Jan 26;135(1):496-505. doi: 10.1111/j.1749-6632.1966.tb45497.x.
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Editorial: Infectious (?) myasthenia.社论:感染性(?)重症肌无力
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Expression of a receptor for IgM by human T cells in vitro.人T细胞在体外表达IgM受体。
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