Leonard Hayley C, Bedford Rachael, Pickles Andrew, Hill Elisabeth L
Department of Psychology, Goldsmiths College, University of London, London, UK.
Biostatistics Department, Institute of Psychiatry, King's College London, London, UK.
Res Autism Spectr Disord. 2015 May;13-14:15-24. doi: 10.1016/j.rasd.2014.12.012. Epub 2015 Mar 12.
The aim of the current paper was to use data from a prospective study to assess the impact of early motor skills on the rate of language development in infants with an older sibling with Autism Spectrum Disorder (ASD), who are at increased risk of developing ASD themselves. Infants were tested prospectively at four points (7, 14, 24 and 36 months), and were assessed for ASD at the last visit. Latent growth curve analysis was used to model rate of language development using the Vineland Adaptive Behavior Scales between 7-36 months in infants at high and low familial risk for ASD. Motor scores from the Mullen Scales of Early Learning at 7 months were used as predictors of language growth. Gross motor scores predicted the subsequent rate of expressive, but not receptive, language development in at-risk siblings who were later diagnosed with ASD. Although the pattern was similar for fine motor skills, the relationship did not reach significance. It seems that early motor delay impacts the rate of development of language, and this may be of particular importance to infants at increased risk of developing ASD.
本文的目的是利用一项前瞻性研究的数据，评估早期运动技能对有患自闭症谱系障碍（ASD）哥哥/姐姐的婴儿语言发育速度的影响，这些婴儿自身患ASD的风险增加。对婴儿在四个时间点（7、14、24和36个月）进行前瞻性测试，并在最后一次访视时评估其是否患有ASD。使用潜在生长曲线分析，以《文兰适应行为量表》为基础，对高家族风险和低家族风险的ASD婴儿在7至36个月期间的语言发育速度进行建模。7个月时《穆伦早期学习量表》的运动得分被用作语言发展的预测指标。粗大运动得分预测了后来被诊断为ASD的高危同胞随后的表达性语言发展速度，但不能预测接受性语言发展速度。虽然精细运动技能的模式相似，但这种关系未达到显著水平。早期运动延迟似乎会影响语言发展速度，这对患ASD风险增加的婴儿可能尤为重要。
