Arifa Mando K, Ephraim Rena, Rajamani Thiruman
Department of Pediatric and Preventive Dentistry, Mahe Institute of Dental Sciences and Hospital, Mahe, Puducherry, India.
Int J Clin Pediatr Dent. 2019 Mar-Apr;12(2):139-144. doi: 10.5005/jp-journals-10005-1603.
The dental caries is not simply a continuous and unidirectional process of the demineralization of the mineral phase, but a cyclic event with periods of demineralizations and remineralisation. The remineralization process is a natural repair mechanism to restore the minerals again, in ionic forms, to the hydroxyapatite (HAP) crystal lattice. It occurs under near-neutral physiological pH conditions whereby calcium and phosphate mineral ions are redeposited within the caries lesion from saliva and plaque fluid resulting in the formation of newer HAP crystals, which are larger and more resistant to acid dissolution. Numerous types of remineralizing agents and remineralizing techniques have been researched and many of them are being used clinically, with significantly predictable positive results. The recent researches on remineralization are based on biomimetic remineralization materials, having the capability to create apatite crystals within the completely demineralized collagen fibers.
Arifa MK, Ephraim R, Recent Advances in Dental Hard Tissue Remineralization: A Review of Literature. Int J Clin Pediatr Dent 2019;12(2):139-144.
龋齿并非仅仅是牙体矿物质相持续且单向脱矿的过程,而是一个存在脱矿和再矿化周期的循环事件。再矿化过程是一种自然修复机制,能以离子形式将矿物质重新还原到羟基磷灰石(HAP)晶格中。它发生在接近中性的生理pH条件下,此时钙和磷酸盐矿物离子从唾液和菌斑液中重新沉积在龋损部位,形成更新的HAP晶体,这些晶体更大且更耐酸溶解。人们已经研究了多种再矿化剂和再矿化技术,其中许多已在临床中使用,并取得了显著可预测的积极效果。近期关于再矿化的研究基于仿生再矿化材料,这种材料能够在完全脱矿的胶原纤维内生成磷灰石晶体。
阿里法·MK,以法莲·R,《牙硬组织再矿化的最新进展:文献综述》。《国际临床儿科牙科学杂志》2019年;12(2):139 - 144。