Centro de Investigacións Científicas Avanzadas (CICA) e Departmento de Química, Facultade de Ciencias, Universidade da Coruña, 15071 A Coruña, Spain.
Mar Drugs. 2020 Jan 16;18(1):59. doi: 10.3390/md18010059.
Mexico is one of the three areas of the world with the greatest terrestrial and cultural biological diversity. The diversity of Mexican medicinal flora has been studied for a long time and several bioactive compounds have been isolated. The investigation of marine resources, and particularly the potential of Mexican marine resources, has not been intensively investigated, even though the Yucatan Peninsula occupies 17.4% of the total of the Mexican coast, with great biological diversity in its coasts and the ocean. There are very few studies on the chemistry of natural products from marine organisms that were collected along the coasts of the Yucatan Peninsula and most of them are limited to the evaluation of the biological activity of their organic extracts. The investigations carried out on marine species from the Yucatan Peninsula resulted in the identification of a wide structural variety of natural products that include polyketides, terpenoids, nitrogen compounds, and biopolymers with cytotoxic, antibacterial, antifouling, and neurotoxic activities. This review describes the literature of bioprospecting and the exploration of the natural product diversity of marine organisms from the coasts of the Yucatan Peninsula up to mid-2019.
墨西哥是世界上生物多样性最丰富的三个地区之一，拥有丰富的陆地和文化生物多样性。对墨西哥药用植物群的多样性进行了长期研究，并分离出了几种生物活性化合物。对海洋资源的调查，特别是墨西哥海洋资源的潜力，并没有得到深入的调查，尽管尤卡坦半岛占据了墨西哥总海岸线的 17.4%，其沿海地区和海洋具有丰富的生物多样性。对从尤卡坦半岛沿海采集的海洋生物的天然产物化学的研究很少，而且大多数研究都局限于评价其有机提取物的生物活性。对尤卡坦半岛海洋物种的调查结果表明，存在广泛的天然产物结构多样性，包括聚酮、萜类、含氮化合物和具有细胞毒性、抗菌、抗污和神经毒性的生物聚合物。本综述描述了截至 2019 年年中对尤卡坦半岛沿海海洋生物的生物勘探和天然产物多样性的文献研究。
