Herff Christian, Krusienski Dean J, Kubben Pieter
Department of Neurosurgery, School of Mental Health and Neurosciences, Maastricht University, Maastricht, Netherlands.
ASPEN Lab, Biomedical Engineering Department, Virginia Commonwealth University, Richmond, VA, United States.
Front Neurosci. 2020 Feb 27;14:123. doi: 10.3389/fnins.2020.00123. eCollection 2020.
Stereotactic electroencephalogaphy (sEEG) utilizes localized, penetrating depth electrodes to measure electrophysiological brain activity. It is most commonly used in the identification of epileptogenic zones in cases of refractory epilepsy. The implanted electrodes generally provide a sparse sampling of a unique set of brain regions including deeper brain structures such as hippocampus, amygdala and insula that cannot be captured by superficial measurement modalities such as electrocorticography (ECoG). Despite the overlapping clinical application and recent progress in decoding of ECoG for Brain-Computer Interfaces (BCIs), sEEG has thus far received comparatively little attention for BCI decoding. Additionally, the success of the related deep-brain stimulation (DBS) implants bodes well for the potential for chronic sEEG applications. This article provides an overview of sEEG technology, BCI-related research, and prospective future directions of sEEG for long-term BCI applications.
立体定向脑电图（sEEG）利用局部穿透深度电极来测量脑电生理活动。它最常用于难治性癫痫病例中致痫区的识别。植入电极通常对一组独特的脑区进行稀疏采样，包括海马体、杏仁核和脑岛等深部脑结构，这些结构无法通过诸如皮层脑电图（ECoG）等表面测量方式捕获。尽管在脑机接口（BCI）的ECoG解码方面有重叠的临床应用和近期进展，但迄今为止，sEEG在BCI解码方面受到的关注相对较少。此外，相关深部脑刺激（DBS）植入的成功预示着慢性sEEG应用的潜力。本文概述了sEEG技术、与BCI相关的研究以及sEEG在长期BCI应用方面未来的潜在发展方向。
