衰老与HIV感染：关注心血管疾病风险
Aging and HIV infection: focus on cardiovascular disease risk.
作者信息
Aberg Judith A
机构信息
Icahn School of Medicine at Mount Sinai and the Mount Sinai Health System, New York, NY, USA.
出版信息
Top Antivir Med. 2020 Jan;27(4):102-105.
Abstract
Effective antiretroviral therapy has extended life expectancy for individuals with HIV. Estimates from 2015 indicate that 47% of persons with HIV in the US were older than 50 years of age and 16% were older than 65 years. These older patients are at increased risk of age-related diseases and conditions. Further, there is substantial evidence that patients with HIV infection accumulate age-related conditions earlier than do those in the general population. There is risk for increased comorbidities and polypharmacy in the aging HIV-infected population. Specific measures for assessing and reducing the risk of cardiovascular disease and other age-related conditions in the aging HIV population are needed. This article summarizes a presentation by Judith A. Aberg, MD, at the International Antiviral Society-USA (IAS-USA) annual continuing education program held in Chicago, Illinois, in May 2019.
摘要
有效的抗逆转录病毒疗法延长了艾滋病病毒感染者的预期寿命。2015年的估计表明，美国47%的艾滋病病毒感染者年龄超过50岁，16%的感染者年龄超过65岁。这些老年患者患与年龄相关疾病和病症的风险增加。此外，有大量证据表明，艾滋病病毒感染者比普通人群更早出现与年龄相关的病症。老年艾滋病病毒感染人群中合并症和多种药物治疗的风险增加。需要采取具体措施来评估和降低老年艾滋病病毒感染人群患心血管疾病和其他与年龄相关病症的风险。本文总结了朱迪思·A·阿伯格医学博士在2019年5月于伊利诺伊州芝加哥举行的美国国际抗病毒学会（IAS-USA）年度继续教育项目上的一次演讲。
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