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酒精对心血管危险因素的影响:是否有新信息?

The Effect of Alcohol on Cardiovascular Risk Factors: Is There New Information?

机构信息

Department of Internal Medicine, Hospital Clinic, Institut d'Investigació Biomèdica August Pi iSunyer(IDIBAPS), University of Barcelona, Villarroel, 170, 08036 Barcelona, Spain.

El Pino Hospital, Avenida Padre Hurtado 13560, San Bernardo, Santiago de Chile, Chile.

出版信息

Nutrients. 2020 Mar 27;12(4):912. doi: 10.3390/nu12040912.

DOI:10.3390/nu12040912
PMID:32230720
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7230699/
Abstract

The effects of alcohol on cardiovascular health are heterogeneous and vary according toconsumption dose and pattern. These effects have classically been described as having a J-shapedcurve, in which low-to-moderate consumption is associated with less risk than lifetime abstention,and heavy drinkers show the highest risk. Nonetheless, the beneficial effects of alcohol have beenquestioned due to the difficulties in establishing a safe drinking threshold. This review focuses onthe association between alcohol consumption and cardiovascular risk factors and the underlyingmechanisms of damage, with review of the literature from the last 10 years.

摘要

酒精对心血管健康的影响是不均匀的,并且根据饮酒剂量和模式而有所不同。这些影响通常被描述为呈“J 形曲线”,其中低至中度饮酒的风险低于终生戒酒,而重度饮酒者的风险最高。尽管如此,由于难以确定安全饮酒阈值,酒精的有益作用受到了质疑。本综述重点关注酒精摄入与心血管危险因素之间的关联以及潜在的损伤机制,并对过去 10 年的文献进行了回顾。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecb3/7230699/c67d36b88b1b/nutrients-12-00912-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecb3/7230699/c67d36b88b1b/nutrients-12-00912-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecb3/7230699/c67d36b88b1b/nutrients-12-00912-g001.jpg

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Antioxid Redox Signal. 2020 Sep 20;33(9):645-662. doi: 10.1089/ars.2019.7922. Epub 2019 Dec 17.
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Sociodemographic and lifestyle factors associated with the neutrophil-to-lymphocyte ratio.与中性粒细胞与淋巴细胞比值相关的社会人口学和生活方式因素。
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营养与心血管疾病的关系远不止超加工食品这一方面。
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Occupational Exposure to Disinfectants and Risk of Incident Cardiovascular Disease among US Nurses: The Nurses' Health Study II.美国护士职业接触消毒剂与心血管疾病发病风险:护士健康研究II
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