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生物电子医学中研究迷走神经的附带益处。

Collateral benefits of studying the vagus nerve in bioelectronic medicine.

作者信息

Pavlov Valentin A

机构信息

1Center for Biomedical Science and Bioelectronic Medicine, The Feinstein Institute for Medical Research, Northwell Health System, Manhasset, NY 11030 USA.

Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11550 USA.

出版信息

Bioelectron Med. 2019 May 16;5:5. doi: 10.1186/s42234-019-0021-3. eCollection 2019.

DOI:10.1186/s42234-019-0021-3
PMID:32232096
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7098239/
Abstract

Studies on the role of the vagus nerve in the regulation of immunity and inflammation have contributed to current preclinical and clinical efforts in bioelectronic medicine. In parallel, this research has generated new insights into the cellular and molecular mechanisms underlying the immunoregulatory functions of the vagus nerve within . The vagus nerve and other cellular components of the inflammatory reflex are implicated in the regulation of bleeding, cancer, obesity, blood pressure, viral infections and other conditions. This broadens scientific horizons and provides new rationale for technological advances and therapeutic implications.

摘要

关于迷走神经在免疫和炎症调节中作用的研究,为当前生物电子医学的临床前和临床研究做出了贡献。与此同时,这项研究对迷走神经在体内免疫调节功能的细胞和分子机制有了新的认识。迷走神经和炎症反射的其他细胞成分与出血、癌症、肥胖、血压、病毒感染及其他病症的调节有关。这拓宽了科学视野,并为技术进步和治疗意义提供了新的理论依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fc0/7098239/4fb6c1b0cd40/42234_2019_21_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fc0/7098239/23c06ffe9a1d/42234_2019_21_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fc0/7098239/4fb6c1b0cd40/42234_2019_21_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fc0/7098239/23c06ffe9a1d/42234_2019_21_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fc0/7098239/4fb6c1b0cd40/42234_2019_21_Fig2_HTML.jpg

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Neuron. 2022 Nov 2;110(21):3627-3644. doi: 10.1016/j.neuron.2022.09.003. Epub 2022 Sep 28.
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