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眼血管炎与抗中性粒细胞胞浆抗体阳性相关。

Eye involvement in ANCA positive vasculitis.

机构信息

Department of Ophthalmology, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Department of Ophthalmology, County Clinical Hospital Cluj-Napoca, Romania.

出版信息

Rom J Ophthalmol. 2020 Jan-Mar;64(1):3-7.

PMID:32292850
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7141924/
Abstract

Vasculitis is a heterogeneous group of diseases that implies the presence of necrosis and inflammation in the walls of blood vessels. The mechanisms involved are the following: immune complexes, endothelial cell antibodies, and anti-lysosomal antibodies. The immune reactions can be triggered by these mechanisms: immune complexes, endothelial cell antibodies, and anti-lysosomal antibodies. Antineutrophil cytoplasmic antibodies (ANCA) have an essential role in the following so-called ANCA+ vasculitis. Regarding this issue, we proposed to present the various aspects of ocular involvement in the ANCA+ vasculitis.

摘要

血管炎是一组异质性疾病,意味着血管壁存在坏死和炎症。涉及的机制如下:免疫复合物、内皮细胞抗体和抗溶酶体抗体。免疫反应可以由这些机制引发:免疫复合物、内皮细胞抗体和抗溶酶体抗体。抗中性粒细胞胞质抗体(ANCA)在以下所谓的 ANCA+血管炎中起着重要作用。关于这个问题,我们提出了在 ANCA+血管炎中眼部受累的各个方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ee5/7141924/7b633c5205f9/RomJOphthalmol-64-3-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ee5/7141924/aa7ea04deda6/RomJOphthalmol-64-3-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ee5/7141924/dbd4d932404b/RomJOphthalmol-64-3-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ee5/7141924/7b633c5205f9/RomJOphthalmol-64-3-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ee5/7141924/aa7ea04deda6/RomJOphthalmol-64-3-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ee5/7141924/dbd4d932404b/RomJOphthalmol-64-3-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ee5/7141924/7b633c5205f9/RomJOphthalmol-64-3-g003.jpg

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J Am Soc Nephrol. 2015 Mar;26(3):537-42. doi: 10.1681/ASN.2013111233. Epub 2014 Oct 16.
2
2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides.2012年修订的国际 Chapel Hill 共识会议血管炎命名法
Arthritis Rheum. 2013 Jan;65(1):1-11. doi: 10.1002/art.37715.
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Antiproteinase 3 antineutrophil cytoplasmic antibodies and disease activity in Wegener granulomatosis.
以进行性双眼表现为特征的抗中性粒细胞胞浆抗体相关性血管炎:一例报告及文献复习
Front Med (Lausanne). 2024 Dec 11;11:1525111. doi: 10.3389/fmed.2024.1525111. eCollection 2024.
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Eye Vis (Lond). 2024 Dec 3;11(1):48. doi: 10.1186/s40662-024-00416-y.
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Granulomatosis with Polyangiitis Discovered Because of Repeated Upper Eyelid Swelling.肉芽肿性多血管炎因反复上眼睑肿胀而被发现。
Medicina (Kaunas). 2024 Sep 23;60(9):1555. doi: 10.3390/medicina60091555.
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