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Coronavirus infections: Epidemiological, clinical and immunological features and hypotheses.冠状病毒感染:流行病学、临床及免疫学特征与假说
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Characteristics of Ocular Findings of Patients With Coronavirus Disease 2019 (COVID-19) in Hubei Province, China.中国湖北省 2019 年冠状病毒病(COVID-19)患者的眼部表现特征。
JAMA Ophthalmol. 2020 May 1;138(5):575-578. doi: 10.1001/jamaophthalmol.2020.1291.
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Estimation of the asymptomatic ratio of novel coronavirus infections (COVID-19).新型冠状病毒感染(COVID-19)无症状感染率的估计。
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Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection.评估 SARS-CoV-2 感染患者的泪液和结膜分泌物中的冠状病毒。
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Br J Ophthalmol. 2020 Mar;104(3):297-298. doi: 10.1136/bjophthalmol-2020-315994.
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结膜炎可能是新冠病毒病(COVID-19)唯一的临床表现和症状。

Conjunctivitis can be the only presenting sign and symptom of COVID-19.

作者信息

Scalinci Sergio Zaccaria, Trovato Battagliola Edoardo

机构信息

DIMEC (Department of Medical and Surgical Sciences), University of Bologna, Bologna, Italy.

出版信息

IDCases. 2020;20:e00774. doi: 10.1016/j.idcr.2020.e00774. Epub 2020 Apr 24.

DOI:10.1016/j.idcr.2020.e00774
PMID:32373467
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7195291/
Abstract

Five cases of non-remitting conjunctivitis turned out to be the sole presenting sign and symptom of COVID-19. These patients tested positive on RT-PCR of naso-pharyngeal swabs and developed no fever, malaise, or respiratory symptoms throughout the course of their illness. They all fully recovered. In the current efforts to fight the spread of this virus, authors want to emphasize that atypical clinical presentations of COVID-19 can occur and a high level of suspicion should be maintained. Ocular involvement and transmission of SARS-CoV-2 should never be overlooked. In fact, conjunctival mucosae are susceptible to respiratory viruses and remain an important point of entry. For this reason, eye protection in the form of goggles or a face shield should be considered essential for all healthcare providers, even when taking care of patients who are not showing typical symptoms of COVID-19.

摘要

五例持续性结膜炎最终成为新冠病毒肺炎的唯一症状表现。这些患者鼻咽拭子的逆转录聚合酶链反应检测呈阳性,且在整个病程中均未出现发热、乏力或呼吸道症状。他们均已完全康复。在当前抗击该病毒传播的努力中,作者们想要强调,新冠病毒肺炎可能会出现非典型临床表现,应保持高度怀疑。绝不应忽视眼部受累及严重急性呼吸综合征冠状病毒2的传播。事实上,结膜黏膜易受呼吸道病毒感染,仍是一个重要的侵入点。因此,对于所有医护人员而言,即使是在护理未表现出新冠病毒肺炎典型症状的患者时,护目镜或面罩形式的眼部防护也应被视为必不可少。