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通过血清抗原酶免疫测定法诊断侵袭性念珠菌病。

Diagnosis of invasive candidosis by enzyme immunoassay of serum antigen.

作者信息

Warren R C, Bartlett A, Bidwell D E, Richardson M D, Voller A, White L O

出版信息

Br Med J. 1977 May 7;1(6070):1183-5. doi: 10.1136/bmj.1.6070.1183.

Abstract

Enzyme immunoassay was used to measure Candida albicans-related antigen in sera of rabbits and mice infected with C albicans. A range of heterologous antigens tested gave no cross reactions. Of the three patients who were investigated and gave positive reactions, two were confirmed as having deep candida infections. Enzyme immunoassay is efficient, simple, and sensitive, and may prove valuable in the early diagnosis of invasive candida infections.

摘要

采用酶免疫测定法检测感染白色念珠菌的家兔和小鼠血清中的白色念珠菌相关抗原。一系列测试的异源抗原未出现交叉反应。在接受调查并呈阳性反应的3例患者中,2例被确诊患有深部念珠菌感染。酶免疫测定法高效、简便且灵敏,可能在侵袭性念珠菌感染的早期诊断中具有重要价值。

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