Department of Radiology and Physical Medicine, University of Granada, E-18016 Granada, Spain.
Clinic Psychology Center Alarcón (CPCA), E-18004 Granada, Spain.
Int J Environ Res Public Health. 2020 May 28;17(11):3831. doi: 10.3390/ijerph17113831.
To analyze the levels of chronic fatigue in Spanish women with endometriosis and its relationship with their psychosocial status and quality of life (QoL).
A total of 230 Spanish women with a clinical diagnosis of endometriosis were recruited. Chronic fatigue (Piper Fatigue Scale) and pelvic pain (Numeric Rating Scale) were evaluated. An on-line battery of validated scales was used to assess psychosocial status [Hospital Anxiety and Depression Scale, Scale for Mood Assessment, Pain Catastrophizing Scale, Pittsburgh Sleep Quality Index, Gastrointestinal Quality of Life Index, Female Sexual Function Index and Medical Outcomes Study-Social Support Survey] and QoL [Endometriosis-Health Profile questionnaire-30]. Associations between fatigue and both psychosocial and QoL outcomes were explored through multivariate regression models.
One-third and one-half of women showed moderate and severe fatigue, respectively. Fatigue was associated with higher anxiety and depression, poorer sleep quality, poorer sexual functioning, worse gastrointestinal health, higher catastrophizing thoughts, higher anger/hostility scores and lower QoL (-values < 0.050). Moreover, fatigue and catastrophizing thoughts showed a mediating effect on the association between pelvic pain and QoL.
This work reveals the important role of fatigue in the association between pain, psychosocial status, and QoL of Spanish women with endometriosis.
分析西班牙子宫内膜异位症女性慢性疲劳的水平及其与社会心理状况和生活质量（QoL）的关系。
共招募了 230 名西班牙子宫内膜异位症的临床诊断女性。评估慢性疲劳（Piper 疲劳量表）和盆腔疼痛（数字评分量表）。使用在线验证的一系列量表评估社会心理状况[医院焦虑和抑郁量表、情绪评估量表、疼痛灾难化量表、匹兹堡睡眠质量指数、胃肠道生活质量指数、女性性功能指数和医疗结果研究-社会支持调查]和 QoL[子宫内膜异位症健康状况问卷-30]。通过多元回归模型探讨疲劳与社会心理和 QoL 结果之间的关系。
三分之一和一半的女性分别表现出中度和重度疲劳。疲劳与更高的焦虑和抑郁、更差的睡眠质量、更差的性功能、更差的胃肠道健康、更高的灾难化思维、更高的愤怒/敌意评分和更低的 QoL 相关（P 值 < 0.050）。此外，疲劳和灾难化思维对盆腔疼痛与 QoL 之间的关联起着中介作用。
这项工作揭示了疲劳在西班牙子宫内膜异位症女性疼痛、社会心理状况和 QoL 之间的关联中的重要作用。
