Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Faculty of Medicine and Health Sciences, Centre for the Evaluation of Vaccination, Vaccine and Infectious Diseases Institute, University of Antwerp, Antwerp, Belgium.
Front Immunol. 2020 Jun 24;11:1282. doi: 10.3389/fimmu.2020.01282. eCollection 2020.
Immunization during pregnancy has been recommended in an increasing number of countries. The aim of this strategy is to protect pregnant women and infants from severe infectious disease, morbidity and mortality and is currently limited to tetanus, inactivated influenza, and pertussis-containing vaccines. There have been recent advancements in the development of vaccines designed primarily for use in pregnant women (respiratory syncytial virus and group B vaccines). Although there is increasing evidence to support vaccination in pregnancy, important gaps in knowledge still exist and need to be addressed by future studies. This collaborative consensus paper provides a review of the current literature on immunization during pregnancy and highlights the gaps in knowledge and a consensus of priorities for future research initiatives, in order to optimize protection for both the mother and the infant.
越来越多的国家推荐孕妇进行免疫接种。该策略的目的是保护孕妇和婴儿免受严重传染病、发病率和死亡率的影响,目前仅限于破伤风、灭活流感和含百日咳疫苗。最近在专为孕妇设计的疫苗开发方面取得了进展(呼吸道合胞病毒和 B 组疫苗)。尽管越来越多的证据支持在怀孕期间接种疫苗,但仍存在重要的知识空白,需要通过未来的研究来解决。这份合作共识文件回顾了目前关于孕妇免疫接种的文献,并强调了知识空白和未来研究计划的优先事项共识,以优化母婴保护。