Department of Pharmaceutical Technology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.
Department of Chemistry, Faculty of Science, Hacettepe University, Ankara, Turkey.
J Drug Target. 2021 Jan;29(1):29-45. doi: 10.1080/1061186X.2020.1797052. Epub 2020 Aug 6.
Synthetic micro/nanomotors (MNMs) are novel, self-propelled nano or microscale devices that are widely used in drug transport, cell stimulation and isolation, bio-imaging, diagnostic and monitoring, sensing, photocatalysis and environmental remediation. Various preparation methods and propulsion mechanisms make MNMs "" nanosystems for the intended purpose or use. As the one of the newest members of nano carriers, MNMs open a new perspective especially for rapid drug transport and gene delivery. Although there exists limited number of studies for drug delivery purposes, existence of supportive data strongly encourages researchers to move on in this field and benefit from the manoeuvre capability of these novel systems. In this article, we reviewed the preparation and propulsion mechanisms of nanomotors in various fields with special attention to drug delivery systems.
合成微/纳米马达（MNMs）是一种新型的自主推进纳米或微尺度装置，广泛应用于药物输送、细胞刺激和分离、生物成像、诊断和监测、传感、光催化和环境修复。各种制备方法和推进机制使 MNMs 成为具有特定目的或用途的“纳米系统”。作为纳米载体的最新成员之一，MNMs 为快速药物输送和基因传递开辟了新的视角。尽管针对药物输送目的的研究数量有限，但存在的支持数据强烈鼓励研究人员在这一领域继续前进，并从这些新型系统的操纵能力中受益。在本文中，我们综述了各种领域的纳米马达的制备和推进机制，特别关注药物输送系统。
