• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

优化控制数学模型以模拟 2019 年冠状病毒病(COVID-19)在印度尼西亚的流行过程。

Optimal control on a mathematical model to pattern the progression of coronavirus disease 2019 (COVID-19) in Indonesia.

机构信息

Department of Statistics, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh, 23111 Indonesia.

Graduate School of Mathematics and Applied Sciences, Universitas Syiah Kuala, Banda Aceh, 23111 Indonesia.

出版信息

Glob Health Res Policy. 2020 Aug 5;5:38. doi: 10.1186/s41256-020-00163-2. eCollection 2020.

DOI:10.1186/s41256-020-00163-2
PMID:32775696
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7402809/
Abstract

BACKGROUND

Understanding the pattern of COVID-19 infection progression is critical for health policymakers. Reaching the exponential peak of cases, flattening the curve, and treating all of the active cases are the keys to success in reducing outbreak transmission. The objective of this study was to determine the most effective model for predicting the peak of COVID-19 in Indonesia, using a deterministic model.

METHODS

The SEI2RS model considers five strategies for control, namely: large-scale social restriction ( ), contact tracing ( ), mass testing ( ) case detection and treatment ( ), and the wearing of face masks ( ) Three scenarios were developed, each differentiated by the controls. The model used April 10, 2020, and December 31, 2020, as the initial and final times.

RESULTS

The simulation results indicated that the peak of COVID-19 cases for scenarios 1, 2, and 3 occur on the 59th day with 33,151 cases, on the 38th day with 37,908 cases, and on the 40th day with 39,305 cases. For all of the scenarios, the decline phase shows a slow downward slope and about 8000 cases of COVID-19 still active by the end of 2020.

CONCLUSION

The study concludes that scenario 2, which consists of large-scale social restriction (), contact tracing (), case detection and treatment (), and the wearing of face masks (), is the most rational scenario to control COVID-19 spreading in Indonesia.

摘要

背景

了解 COVID-19 感染进展的模式对于卫生政策制定者至关重要。达到病例的指数峰值、使曲线变平以及治疗所有活动病例是减少疫情传播成功的关键。本研究的目的是使用确定性模型确定预测印度尼西亚 COVID-19 峰值的最有效模型。

方法

SEI2RS 模型考虑了五种控制策略,即:大规模社会限制()、接触者追踪()、大规模检测()、病例发现和治疗()以及佩戴口罩()。开发了三种情景,每种情景都通过控制措施进行了区分。该模型使用 2020 年 4 月 10 日和 2020 年 12 月 31 日作为初始和最终时间。

结果

模拟结果表明,情景 1、2 和 3 的 COVID-19 病例峰值分别出现在第 59 天,有 33,151 例,第 38 天,有 37,908 例,第 40 天,有 39,305 例。对于所有情景,下降阶段显示出缓慢的下降趋势,到 2020 年底仍有大约 8000 例 COVID-19 活跃病例。

结论

研究得出的结论是,情景 2,即大规模社会限制()、接触者追踪()、病例发现和治疗()以及佩戴口罩(),是控制印度尼西亚 COVID-19 传播的最合理情景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84e7/7404925/f9a3690ec14d/41256_2020_163_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84e7/7404925/40fe1d943d46/41256_2020_163_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84e7/7404925/346dc5bc0878/41256_2020_163_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84e7/7404925/cddfe2789af5/41256_2020_163_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84e7/7404925/f9a3690ec14d/41256_2020_163_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84e7/7404925/40fe1d943d46/41256_2020_163_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84e7/7404925/346dc5bc0878/41256_2020_163_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84e7/7404925/cddfe2789af5/41256_2020_163_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84e7/7404925/f9a3690ec14d/41256_2020_163_Fig4_HTML.jpg

相似文献

1
Optimal control on a mathematical model to pattern the progression of coronavirus disease 2019 (COVID-19) in Indonesia.优化控制数学模型以模拟 2019 年冠状病毒病(COVID-19)在印度尼西亚的流行过程。
Glob Health Res Policy. 2020 Aug 5;5:38. doi: 10.1186/s41256-020-00163-2. eCollection 2020.
2
Optimal control on COVID-19 eradication program in Indonesia under the effect of community awareness.社区意识影响下的印度尼西亚 COVID-19 根除计划的最优控制。
Math Biosci Eng. 2020 Sep 23;17(6):6355-6389. doi: 10.3934/mbe.2020335.
3
Determining the optimal strategy for reopening schools, the impact of test and trace interventions, and the risk of occurrence of a second COVID-19 epidemic wave in the UK: a modelling study.确定英国学校重新开放的最佳策略、检测和追踪干预措施的影响,以及发生第二波 COVID-19 疫情的风险:一项建模研究。
Lancet Child Adolesc Health. 2020 Nov;4(11):817-827. doi: 10.1016/S2352-4642(20)30250-9. Epub 2020 Aug 3.
4
Non Pharmaceutical Interventions for Optimal Control of COVID-19.非药物干预措施以实现 COVID-19 的最佳控制。
Comput Methods Programs Biomed. 2020 Nov;196:105642. doi: 10.1016/j.cmpb.2020.105642. Epub 2020 Jul 7.
5
Impact of early detection and vaccination strategy in COVID-19 eradication program in Jakarta, Indonesia.印度尼西亚雅加达 COVID-19 根除计划中早期检测和疫苗接种策略的影响。
BMC Res Notes. 2021 Apr 12;14(1):132. doi: 10.1186/s13104-021-05540-9.
6
Successful COVID-19 Contact Tracing of Crew from Two Cargo Ships at the Morowali Seaport, Indonesia.印度尼西亚莫罗瓦利(Morowali)海港对两艘货船上的船员进行成功的 COVID-19 接触者追踪。
Disaster Med Public Health Prep. 2023 Jun 22;17:e418. doi: 10.1017/dmp.2023.88.
7
COVID-19 Intervention Scenarios for a Long-term Disease Management.COVID-19 长期疾病管理干预场景。
Int J Health Policy Manag. 2020 Dec 1;9(12):508-516. doi: 10.34172/ijhpm.2020.130.
8
Vaccines alone are no silver bullets: a modeling study on the impact of efficient contact tracing on COVID-19 infection and transmission in Malaysia.仅靠疫苗并非万能:关于高效接触者追踪对马来西亚 COVID-19 感染和传播影响的建模研究。
Int Health. 2023 Jan 3;15(1):37-46. doi: 10.1093/inthealth/ihac005.
9
Positive Correlation Between General Public Knowledge and Attitudes Regarding COVID-19 Outbreak 1 Month After First Cases Reported in Indonesia.公众对 COVID-19 爆发的知识和态度在印度尼西亚首次报告病例后 1 个月呈正相关。
J Community Health. 2021 Feb;46(1):182-189. doi: 10.1007/s10900-020-00866-0.
10
Wearing face masks regardless of symptoms is crucial for preventing the spread of COVID-19 in hospitals.无论有无症状,佩戴口罩对于防止新冠病毒在医院传播至关重要。
Infect Control Hosp Epidemiol. 2021 Jan;42(1):115-116. doi: 10.1017/ice.2020.202. Epub 2020 May 6.

引用本文的文献

1
Mathematical Contact Tracing Models for the COVID-19 Pandemic: A Systematic Review of the Literature.COVID-19大流行的数学接触者追踪模型:文献系统综述
Healthcare (Basel). 2025 Apr 18;13(8):935. doi: 10.3390/healthcare13080935.
2
Evolution of Sequence and Structure of SARS-CoV-2 Spike Protein: A Dynamic Perspective.严重急性呼吸综合征冠状病毒2刺突蛋白的序列与结构演变:动态视角
ACS Omega. 2023 Jun 21;8(26):23283-23304. doi: 10.1021/acsomega.3c00944. eCollection 2023 Jul 4.
3
Strengthening government's response to COVID-19 in Indonesia: A modified Delphi study of medical and health academics.

本文引用的文献

1
Review and analysis of current responses to COVID-19 in Indonesia: Period of January to March 2020.印度尼西亚当前对2019冠状病毒病应对措施的回顾与分析:2020年1月至3月期间
Prog Disaster Sci. 2020 Apr;6:100091. doi: 10.1016/j.pdisas.2020.100091. Epub 2020 Apr 4.
2
Mathematical modeling of the spread of the coronavirus disease 2019 (COVID-19) taking into account the undetected infections. The case of China.考虑未检测到感染情况的2019冠状病毒病(COVID-19)传播的数学模型。以中国为例。
Commun Nonlinear Sci Numer Simul. 2020 Sep;88:105303. doi: 10.1016/j.cnsns.2020.105303. Epub 2020 Apr 30.
3
Commentary on Ferguson, et al., "Impact of Non-pharmaceutical Interventions (NPIs) to Reduce COVID-19 Mortality and Healthcare Demand".
加强印度尼西亚政府对 COVID-19 的应对措施:医学和卫生学术界的修正德尔菲研究。
PLoS One. 2022 Sep 29;17(9):e0275153. doi: 10.1371/journal.pone.0275153. eCollection 2022.
4
Analysis of Supporting Factors Associated with Exclusive Breastfeeding Practice in the Urban Setting during the COVID-19 Pandemic.新冠疫情期间城市地区纯母乳喂养行为相关支持因素分析
Children (Basel). 2022 Jul 19;9(7):1074. doi: 10.3390/children9071074.
5
Mathematical Modeling and Control of COVID-19 Using Super Twisting Sliding Mode and Nonlinear Techniques.利用超扭曲滑模和非线性技术对 COVID-19 的数学建模与控制。
Comput Intell Neurosci. 2022 Jun 30;2022:8539278. doi: 10.1155/2022/8539278. eCollection 2022.
6
Mathematical COVID-19 model with vaccination: a case study in Saudi Arabia.具有疫苗接种的新冠肺炎数学模型:沙特阿拉伯的案例研究。
PeerJ Comput Sci. 2022 May 13;8:e959. doi: 10.7717/peerj-cs.959. eCollection 2022.
7
Modeling of COVID-19 spread with self-isolation at home and hospitalized classes.新型冠状病毒肺炎在家自我隔离和住院病例传播的建模
Results Phys. 2022 May;36:105378. doi: 10.1016/j.rinp.2022.105378. Epub 2022 Mar 5.
8
Global Analysis and Optimal Control Model of COVID-19.COVID-19 的全球分析与最优控制模型。
Comput Math Methods Med. 2022 Jan 27;2022:9491847. doi: 10.1155/2022/9491847. eCollection 2022.
9
The Quality of Life of Coronavirus Disease Survivors Living in Rural and Urban Area of Riau Province, Indonesia.印度尼西亚廖内省农村和城市地区新冠病毒病幸存者的生活质量
Infect Dis Rep. 2022 Jan 7;14(1):33-42. doi: 10.3390/idr14010005.
10
Impact of vaccine supplies and delays on optimal control of the COVID-19 pandemic: mapping interventions for the Philippines.疫苗供应和延迟对 COVID-19 大流行最佳控制的影响:为菲律宾规划干预措施。
Infect Dis Poverty. 2021 Aug 9;10(1):107. doi: 10.1186/s40249-021-00886-5.
评 Ferguson 等人的“减少 COVID-19 死亡率和医疗需求的非药物干预(NPIs)的影响”一文。
Bull Math Biol. 2020 Apr 8;82(4):52. doi: 10.1007/s11538-020-00726-x.
4
A mathematical model for the novel coronavirus epidemic in Wuhan, China.中国武汉新型冠状病毒疫情的数学模型。
Math Biosci Eng. 2020 Mar 11;17(3):2708-2724. doi: 10.3934/mbe.2020148.
5
The effect of control strategies to reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study.控制策略对减少社交接触以控制中国武汉 COVID-19 疫情的效果:建模研究。
Lancet Public Health. 2020 May;5(5):e261-e270. doi: 10.1016/S2468-2667(20)30073-6. Epub 2020 Mar 25.
6
Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2).大量未记录的感染使新型冠状病毒(SARS-CoV-2)迅速传播。
Science. 2020 May 1;368(6490):489-493. doi: 10.1126/science.abb3221. Epub 2020 Mar 16.
7
First two months of the 2019 Coronavirus Disease (COVID-19) epidemic in China: real-time surveillance and evaluation with a second derivative model.中国 2019 年冠状病毒病(COVID-19)疫情前两个月:实时监测与二阶导数模型评估。
Glob Health Res Policy. 2020 Mar 2;5:7. doi: 10.1186/s41256-020-00137-4. eCollection 2020.
8
Mathematical model and intervention strategies for mitigating tuberculosis in the Philippines.菲律宾结核病缓解的数学模型与干预策略。
J Theor Biol. 2018 Apr 14;443:100-112. doi: 10.1016/j.jtbi.2018.01.026. Epub 2018 Feb 3.
9
Optimal tuberculosis prevention and control strategy from a mathematical model based on real data.基于真实数据的数学模型对结核病最优防控策略的研究。
Bull Math Biol. 2014 Jul;76(7):1566-89. doi: 10.1007/s11538-014-9962-6. Epub 2014 May 22.
10
Optimal control strategies and cost-effectiveness analysis of a malaria model.疟疾模型的最优控制策略与成本效益分析
Biosystems. 2013 Feb;111(2):83-101. doi: 10.1016/j.biosystems.2012.09.008. Epub 2013 Jan 8.