Moghadas Sharif Nasrin, Yazdani Negareh, Shahkarami Leila, Ostadi Moghaddam Hadi, Ehsaei Asieh
Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Optometry, Mashhad University of Medical Sciences, Mashhad, Iran.
J Curr Ophthalmol. 2020 Jul 4;32(3):263-267. doi: 10.4103/JOCO.JOCO_7_20. eCollection 2020 Jul-Sep.
To assess refractive error, gender, and age-related differences in corneal topography of a normal population with Oculus Keratograph 4.
This cross-sectional study included a total of 500 normal eyes of 500 individuals with ages ranging from 10 to 70 years. All participants underwent detailed ocular examinations, including visual acuity measurement, slit-lamp examination, and refractive error evaluation. Slit-lamp examination was performed for all individuals to rule out apparent corneal diseases. Corneal topography parameters were assessed using Oculus Keratograph. The data were analyzed based on gender, refractive error, and age groups using independent sample -test and one-way analysis of variance.
Of a total of 500 participants (age: 29.51 ± 11.53 years) recruited for the present study, 66.4% were female, and 33.6% were male. The mean spherical equivalent of refraction was - 0.98 ± 1.65 diopters. Significant differences were noted in steep keratometry ( = 0.035) and corneal astigmatism ( = 0.014) between genders. Assessment of the data based on refractive error revealed significant differences in an index of vertical asymmetry ( < 0.001), index of height asymmetry ( = 0.003), and index of height decentration ( = 0.011). Considering age groups, significant differences were observed in flat keratometry readings ( < 0.001), mean corneal astigmatism ( = 0.02), minimum radius of curvature ( = 0.037), and apex power ( < 0.001).
There was a prominent variation in some topographic parameters based on gender, age, and refractive error. The information on corneal parameters obtained with Oculus Keratograph from normal eyes provides a reference for comparison with diseased corneas.
使用欧几里得角膜地形图仪4评估正常人群角膜地形图的屈光不正、性别和年龄相关差异。
这项横断面研究共纳入了500名年龄在10至70岁之间个体的500只正常眼睛。所有参与者均接受了详细的眼部检查，包括视力测量、裂隙灯检查和屈光不正评估。对所有个体进行裂隙灯检查以排除明显的角膜疾病。使用欧几里得角膜地形图仪评估角膜地形图参数。基于性别、屈光不正和年龄组，使用独立样本t检验和单因素方差分析对数据进行分析。
本研究共招募了500名参与者（年龄：29.51±11.53岁），其中66.4%为女性，33.6%为男性。平均等效球镜度为-0.98±1.65屈光度。男女之间在陡峭角膜曲率（P=0.035）和角膜散光（P=0.014）方面存在显著差异。基于屈光不正对数据进行评估显示，垂直不对称指数（P<0.001）、高度不对称指数（P=0.003）和高度偏心指数（P=0.011）存在显著差异。考虑年龄组，在平坦角膜曲率读数（P<0.001）、平均角膜散光（P=0.02）、最小曲率半径（P=0.037）和顶点屈光力（P<0.001）方面观察到显著差异。
基于性别、年龄和屈光不正，一些地形图参数存在显著差异。从正常眼睛使用欧几里得角膜地形图仪获得的角膜参数信息为与患病角膜进行比较提供了参考。
