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刺梨叶提取物的抗菌及体外抗痴呆作用

Antibacterial and in vitro antidementia effects of aronia () leaf extracts.

作者信息

Kim Sang-Soon, Shin Youngjae

机构信息

Department of Food Engineering, Dankook University, Cheonan, Chungnam 31116 Republic of Korea.

出版信息

Food Sci Biotechnol. 2020 May 22;29(9):1295-1300. doi: 10.1007/s10068-020-00774-y. eCollection 2020 Sep.

DOI:10.1007/s10068-020-00774-y
PMID:32802569
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7406618/
Abstract

This study investigated the antibacterial and in vitro antidementia effects of aronia () leaf extracts from 3 cultivars (Nero, Viking, and McKenzie) collected at three different stages of maturity (young, harvest, and old). was susceptible to the old leaves of cultivars McKenzie and Nero, whereas O157:H7, Typhimurium, and were not inhibited by any of the extracts. Growth of was inhibited by cv. McKenzie, resulting in increased lag time, whereas Nero had both an inhibitory and an inactivation effect. Except for cv. Viking at harvest stage, the acetylcholinesterase and butyrylcholinesterase inhibitory activity of aronia leaf extracts were about 60-70 and 70-80%, respectively. Therefore, aronia leaf is a natural resource with a potentially potent antidementia effect, besides antibacterial activity.

摘要

本研究调查了从3个品种(尼禄、维京和麦肯齐)的野生黑樱()叶片中提取的提取物在三个不同成熟阶段(幼叶、收获期叶和老叶)的抗菌和体外抗痴呆作用。 对品种麦肯齐和尼禄的老叶敏感,而O157:H7、鼠伤寒沙门氏菌和 均不受任何提取物的抑制。 品种麦肯齐的提取物抑制了 的生长,导致延迟期延长,而尼禄品种的提取物既有抑制作用又有灭活作用。除了收获期的维京品种外,野生黑樱叶片提取物的乙酰胆碱酯酶和丁酰胆碱酯酶抑制活性分别约为60 - 70%和70 - 80%。因此,除抗菌活性外,野生黑樱叶是一种具有潜在强效抗痴呆作用的自然资源。

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