Chaari Ali, Bendriss Ghizlane, Zakaria Dalia, McVeigh Clare
Premedical Department, Weill Cornell Medicine, Qatar Foundation, Education City, Doha, Qatar.
Front Public Health. 2020 Aug 27;8:476. doi: 10.3389/fpubh.2020.00476. eCollection 2020.
The new coronavirus pandemic continues to spread causing further public health, social, and economic issues. The disparities in the rates of death between countries poses questions about the importance of lifestyle habits and the immune status of populations. An exploration of dietary habits and COVID-19-related death might unravel associations between these two variables. Indeed, while both nutritional excess and deficiency are associated with immunodeficiency, adequate nutrition leading to an optimally functioning immune system may be associated with better outcomes with regards to preventing infection and complications of COVID-19, as well as developing a better immune response to other pathogenic viruses and microorganisms. This article outlines the key functions of the immune system and how macronutrients, micronutrients, and metabolites from the gut microbiome can be essential in the development of an efficient immune system. In addition, the effects of intermittent fasting on the inflammatory state as well as metabolic parameters will be discussed.
新型冠状病毒大流行仍在持续蔓延，引发了更多公共卫生、社会和经济问题。各国之间的死亡率差异引发了关于生活方式习惯和人群免疫状态重要性的疑问。对饮食习惯与新冠相关死亡情况的探究可能会揭示这两个变量之间的关联。确实，虽然营养过剩和营养缺乏都与免疫缺陷有关，但充足的营养能使免疫系统功能达到最佳状态，这可能在预防新冠感染及并发症方面带来更好的结果，也有助于对其他致病病毒和微生物产生更好的免疫反应。本文概述了免疫系统的关键功能，以及常量营养素、微量营养素和肠道微生物群代谢产物在高效免疫系统发育中的重要性。此外，还将讨论间歇性禁食对炎症状态以及代谢参数的影响。
