白色念珠菌对酮康唑敏感性的肉汤稀释试验
Broth dilution testing of Candida albicans susceptibility to ketoconazole.
作者信息
Hughes C E, Bennett R L, Beggs W H
出版信息
Antimicrob Agents Chemother. 1987 Apr;31(4):643-6. doi: 10.1128/AAC.31.4.643.
Abstract
We performed a detailed investigation of the kinetics of ketoconazole activity in the setting of broth dilution testing of Candida albicans susceptibility. Turbidimetric readings reflected parallel quantitative colony counts. The method of endpoint determination markedly affected the results. Determinations of 50% inhibitory concentrations clearly separated the ketoconazole-resistant strains from the susceptible strains.
摘要
我们在白色念珠菌敏感性肉汤稀释试验中，对酮康唑活性动力学进行了详细研究。比浊读数反映了平行的定量菌落计数。终点测定方法对结果有显著影响。50%抑制浓度的测定清晰地将酮康唑耐药菌株与敏感菌株区分开来。
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