Mangiavillano Benedetto, Sosa-Valencia Leonardo, Deprez Pierre, Eisendrath Pierre, Robles-Medranda Carlos, Eusebi Leonardo H, Di Leo Milena, Auriemma Francesco, Bianchetti Mario, Anderloni Andrea, Carrara Silvia, Repici Alessandro
Gastrointestinal Endoscopy Unit - Humanitas Mater Domini - Castellanza (VA), Italy.
Humamitas University.
Endosc Int Open. 2020 Oct;8(10):E1315-E1320. doi: 10.1055/a-1221-4578. Epub 2020 Sep 22.
Pancreatic cancer represents the fourth most common cause of cancer-related deaths in Western countries and the need of a low-risk investigation to obtain an accurate histopathological diagnosis has become increasingly pressing. Endoscopic ultrasonography (EUS) with fine-needle aspiration (FNA) is the standard method for obtaining samples from pancreatic masses. In recent years, there has been an increasing need to obtain histological specimens during EUS procedures, rather than cytological ones, to guide oncological treatment options, leading to the so-call "FNB concept." Different needles have been developed for fine-needle biopsy (FNB) in recent years, enabling acquisition of larger specimens on which to perform histological and molecular analyses. The aim of this narrative review was to assess the role of EUS-guided FNA and FNB in patients with pancreatic masses, and to identify which needle and which acquisition technique should be used to improve tissue acquisition.
在西方国家，胰腺癌是癌症相关死亡的第四大常见原因，因此，通过低风险检查以获得准确的组织病理学诊断的需求日益迫切。内镜超声检查（EUS）结合细针穿刺抽吸（FNA）是从胰腺肿块获取样本的标准方法。近年来，越来越需要在EUS检查过程中获取组织学标本而非细胞学标本，以指导肿瘤治疗方案的选择，从而产生了所谓的“FNB概念”。近年来，已开发出不同的针用于细针活检（FNB），能够获取更大的标本以进行组织学和分子分析。本叙述性综述的目的是评估EUS引导下FNA和FNB在胰腺肿块患者中的作用，并确定应使用哪种针和哪种采集技术来改善组织获取。
