De Sandip, Kitsou Chrysoula, Sonenshine Daniel E, Pedra Joao H F, Fikrig Erol, Kassis Judith A, Pal Utpal
Department of Veterinary Medicine, University of Maryland, College Park, MD, USA.
Laboratory for Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA; Department of Biological Sciences, Old Dominion University, Norfolk, VA, USA.
Trends Genet. 2021 Jan;37(1):8-11. doi: 10.1016/j.tig.2020.09.012. Epub 2020 Oct 2.
Ticks exist across diverse environments and transmit numerous pathogens. Due to their long and unique life cycles, these arthropods likely evolved robust epigenetic mechanisms that provide sustainable responses and buffers against extreme environmental conditions. Herein, we highlight how the study of the epigenetic basis of tick biology and vectorial capacity will enrich our knowledge of tick-borne infections.
蜱虫存在于各种不同的环境中,并传播多种病原体。由于其漫长而独特的生命周期,这些节肢动物可能进化出了强大的表观遗传机制,以提供对极端环境条件的可持续反应和缓冲。在此,我们强调对蜱虫生物学和传播能力的表观遗传基础的研究将如何丰富我们对蜱传感染的认识。