R&D organisation, ICAR- National Research Centre on Meat , Hyderabad, India.
Department of Veterinary Public Health, College of Veterinary and Animal Sciences , Wayanad, India.
Hum Vaccin Immunother. 2020 Dec 1;16(12):3023-3033. doi: 10.1080/21645515.2020.1810496. Epub 2020 Oct 29.
Severe acute respiratory syndrome Coronavirus- 2 (SARS-CoV-2), the etiological agent of the novel coronavirus disease (COVID-19), has posed a great public health threat to the global community as a pandemic. The origin of the virus has been linked to animals, through a yet-to-be-identified intermediate host. The disease is transmitted to humans mainly through inhalation or contact with infected droplets. The variable clinical presentation of COVID-19 includes fever, cough, sore throat, breathlessness, fatigue and malaise; however, cutaneous, ocular, neurological, and gastrointestinal manifestations have also been reported. There is an urgent need to strengthen One Health surveillance, intervention, and management strategies to understand the ecology of coronaviruses and to prevent epidemics in the future. Global attention toward the development of treatments, immunotherapies, vaccines, and control options to combat the COVID-19 pandemic has been on an increasing trend. Here, we review the current epidemiological status, public health concerns, and mitigation strategies for COVID-19.
严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）是新型冠状病毒病（COVID-19）的病原体，作为一种大流行疾病，对全球社会构成了巨大的公共卫生威胁。病毒的起源与动物有关，通过一个尚未确定的中间宿主。该疾病主要通过吸入或接触感染飞沫传播给人类。COVID-19 的临床表现多样，包括发热、咳嗽、咽痛、呼吸困难、乏力和不适；然而，也有报道称存在皮肤、眼部、神经和胃肠道表现。迫切需要加强“同一健康”监测、干预和管理策略，以了解冠状病毒的生态系统，防止未来的流行。全球对开发治疗方法、免疫疗法、疫苗和控制措施以应对 COVID-19 大流行的关注度一直在上升。在这里，我们回顾了 COVID-19 的当前流行病学状况、公共卫生关注和缓解策略。
