Suppr超能文献

牙周袋与 COVID-19:二者之间是否存在关联?

Periodontal pocket and COVID-19: Could there be a possible link?

机构信息

Nirupa's DENTAL ZONE, Nallagandla, Hyderabad, Telangana 500019, India.

出版信息

Med Hypotheses. 2021 Jan;146:110355. doi: 10.1016/j.mehy.2020.110355. Epub 2020 Nov 1.

Abstract

COVID-19 is the emerging health emergency ruining the well being of individuals and devastating the global economies. Sustained research focusing on the virus has been on throughout the world. However, no definitive remedies have yet been derived in the containment of the virus. Steady knowledge on the pathogenesis of the virus has revealed certain consistent features specific to the disease which includes massive destruction of the lung due to the presence of excessive angiotensin-converting enzyme receptors (ACE2) which are essential for the viral entry inside the host. Once, access is gained multiplication occurs resulting in suppressing the immune response of the body against the virus. Henceforth, the equilibrium of the host is disrupted leading to manifestation of the disease. The Periodontal pocket also presents with pathology very much similar to COVID-19 and a possibility of dual role can be thought of pertaining to aspects of Periodontal Medicine.

摘要

COVID-19 是一场新兴的卫生紧急事件,它正在破坏个人的健康并摧毁全球经济。全世界一直在对该病毒进行持续的研究。然而,在控制该病毒方面尚未得出明确的治疗方法。对病毒发病机制的持续了解揭示了该病的某些特定特征,包括由于大量存在对病毒进入宿主至关重要的血管紧张素转换酶受体 (ACE2) 而导致的肺部大量破坏。一旦进入,就会发生增殖,从而抑制身体对病毒的免疫反应。因此,宿主的平衡被打破,导致疾病的发生。牙周袋也表现出与 COVID-19 非常相似的病理学特征,因此可以考虑牙周医学方面的双重作用。

相似文献

1
Periodontal pocket and COVID-19: Could there be a possible link?
Med Hypotheses. 2021 Jan;146:110355. doi: 10.1016/j.mehy.2020.110355. Epub 2020 Nov 1.
3
ACE2: from protection of liver disease to propagation of COVID-19.
Clin Sci (Lond). 2020 Dec 11;134(23):3137-3158. doi: 10.1042/CS20201268.
6
Genomic, epigenomic, and immune subtype analysis of CTSL/B and SARS-CoV-2 receptor ACE2 in pan-cancer.
Aging (Albany NY). 2020 Nov 20;12(22):22370-22389. doi: 10.18632/aging.104147.
7
The pivotal link between ACE2 deficiency and SARS-CoV-2 infection.
Eur J Intern Med. 2020 Jun;76:14-20. doi: 10.1016/j.ejim.2020.04.037. Epub 2020 Apr 20.
8
Angiotensin-converting enzyme 2: A protective factor in regulating disease virulence of SARS-COV-2.
IUBMB Life. 2020 Dec;72(12):2533-2545. doi: 10.1002/iub.2391. Epub 2020 Oct 8.
9
Is highly expressed ACE 2 in pregnant women "a curse" in times of COVID-19 pandemic?
Life Sci. 2021 Jan 1;264:118676. doi: 10.1016/j.lfs.2020.118676. Epub 2020 Oct 28.

引用本文的文献

2
The Role of the Plasminogen/Plasmin System in Inflammation of the Oral Cavity.
Cells. 2023 Jan 30;12(3):445. doi: 10.3390/cells12030445.
5
Microscopic observations of SARS-CoV-2 like particles in different oral samples.
Eur J Oral Sci. 2022 Dec;130(6):e12903. doi: 10.1111/eos.12903. Epub 2022 Nov 20.
6
Periodontitis and coronavirus disease 2019.
Periodontol 2000. 2022 Jun;89(1):207-214. doi: 10.1111/prd.12434. Epub 2022 Mar 4.
7
Impact of COVID-19 on Periodontitis and Peri-Implantitis: A Narrative Review.
Front Oral Health. 2022 Feb 10;3:822824. doi: 10.3389/froh.2022.822824. eCollection 2022.
8
COVID-19 Pandemic and Periodontal Practice: The Immunological, Clinical, and Economic Points of View.
Biomed Res Int. 2022 Jan 13;2022:3918980. doi: 10.1155/2022/3918980. eCollection 2022.
9
Periodontal Inflammation and Systemic Diseases: An Overview.
Front Physiol. 2021 Oct 27;12:709438. doi: 10.3389/fphys.2021.709438. eCollection 2021.
10
Virucidal efficacy of chlorhexidine: a systematic review.
Odontology. 2022 Apr;110(2):376-392. doi: 10.1007/s10266-021-00660-x. Epub 2021 Oct 12.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验