Jain A, Kumar L, Kaur J, Baisla T, Goyal P, Pandey A K, Das A, Parashar L
Department of ENT, Employees' State Insurance Corporation ('ESIC') Medical College and Hospital, Faridabad, India.
Department of Community Medicine, Employees' State Insurance Corporation ('ESIC') Medical College and Hospital, Faridabad, India.
J Laryngol Otol. 2020 Nov 16:1-5. doi: 10.1017/S0022215120002467.
To evaluate the occurrence, clinical course and outcomes of olfactory and gustatory dysfunction in patients with laboratory confirmed coronavirus disease 2019 infection.
This is a prospective cross-sectional study of patients diagnosed with coronavirus disease 2019 infection by reverse transcription polymerase chain reaction over two months. The epidemiological and clinical outcomes studied were: age, sex, general symptoms, and olfactory and taste dysfunction.
A total of 410 coronavirus disease 2019 infected patients were included in the study, with 262 males (63.9 per cent) and 148 females (36.1 per cent). Ninety-nine patients (24.1 per cent) reported chemosensory dysfunction, of which 85 patients (20.7 per cent) reported both olfactory and taste dysfunction. Olfactory and taste dysfunction were proportionally more common in females. The mean duration of olfactory and taste dysfunction was 4.9 days, with a range of 2-15 days.
Olfactory and taste dysfunction are prevalent symptoms in coronavirus disease 2019 patients. In this study, they were more common in females than males. The occurrence of such dysfunctions is lower in the Indian population than in the European population.
评估实验室确诊的2019冠状病毒病感染患者嗅觉和味觉功能障碍的发生率、临床病程及结局。
这是一项对通过逆转录聚合酶链反应确诊为2019冠状病毒病感染的患者进行的为期两个月的前瞻性横断面研究。所研究的流行病学和临床结局包括：年龄、性别、一般症状以及嗅觉和味觉功能障碍。
共有410例2019冠状病毒病感染患者纳入研究，其中男性262例（63.9%），女性148例（36.1%）。99例患者（24.1%）报告有化学感觉功能障碍，其中85例患者（20.7%）报告有嗅觉和味觉功能障碍。嗅觉和味觉功能障碍在女性中比例更高。嗅觉和味觉功能障碍的平均持续时间为4.9天，范围为2至15天。
嗅觉和味觉功能障碍是2019冠状病毒病患者的常见症状。在本研究中，它们在女性中比男性更常见。此类功能障碍在印度人群中的发生率低于欧洲人群。
