Birla Ravi K
BIOLIFE4D, Houston, TX, United States.
Front Cardiovasc Med. 2020 Nov 3;7:591581. doi: 10.3389/fcvm.2020.591581. eCollection 2020.
The field of ventricle tissue engineering is focused on bioengineering highly functioning left ventricles that can be used as model systems for basic cardiology research and for cardiotoxicity testing. In this article, we review the current state of the art in the field of ventricle tissue engineering and discuss different strategies that have been used to bioengineer ventricles. Based on this body of literature, there are now common themes in the field that provide guidance for future directives, also presented in this article.
心室组织工程领域专注于生物工程构建高功能的左心室,这些左心室可作为基础心脏病学研究和心脏毒性测试的模型系统。在本文中,我们综述了心室组织工程领域的当前技术水平,并讨论了用于生物工程构建心室的不同策略。基于这一文献体系,该领域目前存在一些共同主题,可为未来的研究方向提供指导,本文也将予以介绍。