Michieletto Davide
School of Physics and Astronomy, University of Edinburgh, Peter Guthrie Tait Road, Edinburgh EH9 3FD, UK.
MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.
Entropy (Basel). 2020 Oct 6;22(10):1130. doi: 10.3390/e22101130.
Systems of "living" polymers are ubiquitous in industry and are traditionally realised using surfactants. Here I first review the theoretical state-of-the-art of living polymers and then discuss non-equilibrium extensions that may be realised with advanced synthetic chemistry or DNA functionalised by proteins. These systems are not only interesting in order to realise novel "living" soft matter but can also shed insight into how genomes are (topologically) regulated in vivo.
“活性”聚合物体系在工业中无处不在,传统上是使用表面活性剂来实现的。在这里,我首先回顾活性聚合物的理论前沿,然后讨论通过先进的合成化学或蛋白质功能化的DNA可能实现的非平衡扩展。这些体系不仅对于实现新型“活性”软物质很有趣,而且还可以深入了解基因组在体内是如何(从拓扑学角度)受到调控的。