Suppr超能文献

新冠病毒(COVID-19):爆发规模越大,R 值越低。

COVID-19: R is lower where outbreak is larger.

机构信息

Department of Economics and Management, University of Parma, Via J. Kennedy, 6, 43125 Parma, Italy.

Department of Economics and Finance, Università Cattolica del Sacro Cuore, Via Necchi, 5, 20123, Milano, Italy.

出版信息

Health Policy. 2021 Feb;125(2):141-147. doi: 10.1016/j.healthpol.2020.10.017. Epub 2020 Nov 8.

Abstract

We use daily data from Lombardy, the Italian region most affected by the COVID-19 outbreak, to calibrate a SIR model on each municipality. Municipalities with a higher initial number of cases feature a lower rate of diffusion, not attributable to herd immunity: there is a robust and strongly significant negative correlation between the estimated basic reproduction number (R) and the initial outbreak size. This represents novel evidence of the prevalence-response elasticity in a cross-sectional setting, characterized by a same health system and homogeneous social distancing regulations. By ruling out alternative explanations, we conclude that a higher number of cases causes changes of behavior, such as a more strict adoption of social distancing measures among the population, that reduce the spread. This finding calls for the distribution of detailed epidemiological data to populations affected by COVID-19 outbreaks.

摘要

我们利用意大利受 COVID-19 疫情影响最严重的伦巴第大区的日常数据,为每个自治市校准 SIR 模型。初始病例数较高的自治市扩散率较低,这并非归因于群体免疫:估计的基本繁殖数 (R) 与初始疫情规模之间存在稳健且具有统计学显著意义的负相关关系。这在具有相同卫生系统和同质化社会隔离规定的横截面上,代表了流行-反应弹性的新证据。通过排除其他解释,我们得出结论,更多的病例会导致行为的改变,例如人口中更严格地采取社会隔离措施,从而减少传播。这一发现呼吁向受 COVID-19 疫情影响的人群分发详细的流行病学数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40a1/7649031/24cdfdb6c533/gr1_lrg.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验