Nagata Ryoko, Ohsumi Tatsuya, Takenaka Shoji, Noiri Yuichiro
Division of Cariology, Operative Dentistry and Endodontics, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8514, Japan.
Pathogens. 2020 Dec 24;10(1):10. doi: 10.3390/pathogens10010010.
In Japan, gastric infection prevalence has markedly decreased with socioeconomic development. We aimed to investigate the prevalence of oral in Japanese adults in 2020 by sex, age, sampling site, and medical history. Unstimulated saliva, supragingival biofilm, and tongue coating were obtained from 88 subjects-with no complaints of upper digestive symptoms-attending a dentist's office for dental check-up or disorders. Supragingival biofilm was collected from the upper incisors, lower incisors, upper right molars and lower left molars to analyze the characteristic distribution. Oral was detected using nested polymerase chain reaction. Oral prevalence did not statistically differ by sex or age. Supragingival biofilm (30.7%) was the most common oral niche; it was also detected in 4.5% of saliva and 2.3% of tongue samples. The lower incisor was the most common site among the supragingival biofilm samples, followed by the upper incisors, lower left molars, and upper right molars. Oral DNA was frequently detected in patients with a history of gastric infection. Oral has a characteristic distribution independent of sex and age, suggesting that it is part of the normal microflora in the adult oral cavity.
在日本，随着社会经济发展，胃部感染患病率显著下降。我们旨在按性别、年龄、采样部位和病史调查2020年日本成年人口腔感染的患病率。从88名无上部消化症状主诉、前往牙医诊所进行牙齿检查或治疗疾病的受试者中获取非刺激性唾液、龈上生物膜和舌苔。从上门牙、下门牙、右上磨牙和左下磨牙采集龈上生物膜，以分析其特征分布。使用巢式聚合酶链反应检测口腔感染。口腔感染患病率在性别或年龄上无统计学差异。龈上生物膜（30.7%）是最常见的口腔感染部位；在4.5%的唾液和2.3%的舌苔样本中也检测到了。在龈上生物膜样本中，下门牙是最常见的部位，其次是上门牙、左下磨牙和右上磨牙。有胃部感染病史的患者中经常检测到口腔感染DNA。口腔感染具有独立于性别和年龄的特征分布，表明它是成人口腔正常微生物群的一部分。
