Faculty of Applied Sciences, UCSI University, No. 1, Jalan Menara Gading, UCSI Heights, 56000, Cheras, Kuala Lumpur, Malaysia.
Biorefinery and Bioprocess Engineering Laboratory, Department of Chemical Engineering and Materials Science, Yuan Ze University, Chungli, Taoyuan, 320, Taiwan.
World J Microbiol Biotechnol. 2021 Jan 4;37(1):12. doi: 10.1007/s11274-020-02967-3.
Carotenoids are a diverse group of lipid-soluble pigments that exhibit potent biological activities such as antioxidant, anti-inflammatory, and provitamin A activities. The potent health benefits of carotenoids result in the surge in the market demands for carotenoids, especially natural carotenoids from sustainable sources. Microbial carotenoids have attracted considerable interests for many industrial applications because of the low costs and ease of scaling-up with shorter production time. There is a growing interest in the search of new and sustainable microbial sources and cost-efficient production strategies following the high economical values and vast commercial applications of carotenoids. This article presents a review on the industrial production strategies of microbial carotenoids from microalgae, fungi, and bacteria sources. The industrial significance of the mass production of microbial carotenoids is also discussed. The structure, classification, and biosynthesis pathway of the carotenoids are also presented in this review.
类胡萝卜素是一组具有不同结构的脂溶性色素,具有强大的生物活性,如抗氧化、抗炎和维生素 A 前体活性。类胡萝卜素具有强大的健康益处,导致市场对类胡萝卜素的需求激增,特别是来自可持续来源的天然类胡萝卜素。由于成本低、生产时间短、易于扩大规模,微生物类胡萝卜素在许多工业应用中引起了相当大的兴趣。随着类胡萝卜素的高经济价值和广泛的商业应用,人们越来越关注寻找新的和可持续的微生物来源和具有成本效益的生产策略。本文综述了从微藻、真菌和细菌来源生产微生物类胡萝卜素的工业生产策略。本文还讨论了微生物类胡萝卜素大规模生产的工业意义。本文还介绍了类胡萝卜素的结构、分类和生物合成途径。