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脊髓损伤的结局:世界神经外科联合会脊柱委员会建议

Outcomes of Spinal Cord Injury: WFNS Spine Committee Recommendations.

作者信息

Parthiban Jutty, Zileli Mehmet, Sharif Salman Yousuf

机构信息

Department of Neurosurgery, Kovai Medical Center Hospital, Coimbatore, India.

Department of Neurosurgery, Ege University, Izmir, Turkey.

出版信息

Neurospine. 2020 Dec;17(4):809-819. doi: 10.14245/ns.2040490.245. Epub 2020 Dec 31.

Abstract

This comprehensive review article aims to provide some definitive statements on the factors like clinical syndromes, radiological findings, and decompressive surgery, that may influence the outcomes in cervical spinal cord injury management. Literature search on these factors published in the last decade were analyzed and definite statements prepared and voted for consensus opinion by the WFNS Spine Committee members and experts in this field at a meeting in Moscow in June 2019 using Delphi method. This was re-evaluated in a meeting in Pakistan in November 2019. Finally, the consensus statements were brought out as recommendations by the committee to the world literature. Traumatic Spinal Cord Syndromes have good prognosis except in elderly and when the presenting neurological deficit was very poor. Though conservative management provides satisfactory results, results can be improved with surgery when instability and progressive compression was present. Locked facet with spinal cord injury denotes poor prognosis. Magnetic resonance imaging T2 imaging is the essential prognostic indicator that apart from sagittal grade, length of injury, maximum canal compromise, maximum spinal cord compression, axial grading (BASIC) score. Diffusion tensor imaging is the next promising predictor in the pipeline. Decompressive surgery when done earlier especially within 24 hours of injury provides better result and there is no clear evidence to show medical management is better or equivalent to delayed surgical management. Clinical syndromes, radiological syndromes, and surgical decompression have strong impact on the out comes in the management of cervical spinal cord injury. Our comprehensive review and final recommendations on this subject will be of great importance in understanding the complex treatment methods in use.

摘要

这篇综述文章旨在就临床综合征、影像学表现和减压手术等可能影响颈脊髓损伤治疗结果的因素给出一些明确的阐述。对过去十年发表的关于这些因素的文献进行了分析,并由世界神经外科联合会(WFNS)脊柱委员会成员和该领域专家于2019年6月在莫斯科的一次会议上采用德尔菲法编写了明确的阐述并投票表决以达成共识意见。2019年11月在巴基斯坦的一次会议上对其进行了重新评估。最后,委员会将共识声明作为建议呈现给世界文献。创伤性脊髓综合征预后良好,但老年人以及初始神经功能缺损非常严重时除外。虽然保守治疗能取得满意效果,但存在不稳定和进行性压迫时,手术可改善治疗结果。伴有脊髓损伤的小关节交锁预示预后不良。磁共振成像T2像除矢状位分级、损伤长度、椎管最大狭窄、脊髓最大受压、轴向分级(BASIC)评分外,是重要的预后指标。弥散张量成像则是接下来有前景的预测指标。早期尤其是在损伤后24小时内进行减压手术效果更好,且没有明确证据表明药物治疗优于或等同于延迟手术治疗。临床综合征、影像学综合征和手术减压对颈脊髓损伤的治疗结果有重大影响。我们关于该主题的全面综述和最终建议对于理解正在使用的复杂治疗方法将非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee69/7788418/dd15bea1ab23/ns-2040490-245f1.jpg

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