Department of Orthopaedics, Leiden University Medical Center, Leiden.
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden.
Acta Orthop. 2021 Jun;92(3):280-284. doi: 10.1080/17453674.2021.1876998. Epub 2021 Jan 22.
Background and purpose - A lifetime perspective on revision risks is needed for optimal timing of arthroplasty in osteoarthritis (OA) patients, weighing the benefit of total hip arthroplasty/total knee arthroplasty (THA/TKA) against the risk of revision, after which outcomes are less favorable. Therefore, we provide population-based 10-year cumulative revision risks stratified by joint, sex, fixation type, and age.Patients and methods - Data from the Dutch Arthroplasty Register (LROI) was used. Primary THAs and TKAs for OA between 2007 and 2018 were included, except metal-on-metal prostheses or hybrid/reversed hybrid fixation. Revision surgery was defined as any change of 1 or more prosthesis components. The 10-year cumulative revision risks were calculated stratified by joint, age, sex, at primary arthroplasty, and fixation type (cemented/uncemented), taking into account mortality as a competing risk. We estimated the percentage of potentially avoidable revisions assuming all OA patients aged < 75 received primary THA/TKA 5 years later while keeping age-specific 10-year revision risks constant.Results - 214,638 primary THAs and 211,099 TKAs were included, of which 31% of THAs and 95% of TKAs were cemented. The 10-year cumulative revision risk varied between 1.6% and 13%, with higher risks in younger age categories. Delaying prosthesis placement by 5 years could potentially avoid 23 (3%) THA and 162 (17%) TKA revisions.Interpretation - Cumulative 10- year revision risk varied considerably by age in both fixation groups, which may be communicated to patients and used to guide timing of surgery.
背景与目的-对于骨关节炎(OA)患者,需要从终身角度考虑翻修风险,权衡全髋关节置换术/全膝关节置换术(THA/TKA)的获益与翻修风险,因为翻修后结局不太理想。因此,我们提供了基于人群的 10 年累积翻修风险,按关节、性别、固定类型和年龄分层。
患者和方法-使用荷兰关节置换登记处(LROI)的数据。纳入了 2007 年至 2018 年期间因 OA 行初次 THA 和 TKA 的患者,但不包括金属对金属假体或混合/反向混合固定。翻修手术定义为任何 1 个或多个假体部件的更换。考虑到死亡率是一种竞争风险,按关节、初次置换时的年龄、性别和固定类型(骨水泥固定/非骨水泥固定)分层计算 10 年累积翻修风险。我们假设所有<75 岁的 OA 患者都将初次 THA/TKA 推迟 5 年,同时保持特定年龄组的 10 年翻修风险不变,以此来估计潜在可避免的翻修比例。
结果-共纳入 214638 例初次 THA 和 211099 例初次 TKA,其中 31%的 THA 和 95%的 TKA 为骨水泥固定。10 年累积翻修风险在 1.6%至 13%之间,年轻患者风险更高。将假体放置推迟 5 年可能会避免 23 例(3%)THA 和 162 例(17%)TKA 翻修。
结论-在两组固定患者中,10 年累积翻修风险在不同年龄组之间差异较大,这可能有助于与患者沟通,并用于指导手术时机。