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哪些因素与慢性肌肉骨骼疼痛患者的健康相关生活质量有关?初级保健中的横断面研究。

What factors are associated with health-related quality of life among patients with chronic musculoskeletal pain? A cross-sectional study in primary health care.

机构信息

Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), P.O. Box 8905, 7491, Trondheim, Norway.

Department of Obstetrics and Gynaecology, St. Olavs Hospital, Trondheim University Hospital, P.O Box 3250, Trondheim, Norway.

出版信息

BMC Musculoskelet Disord. 2021 Jan 22;22(1):102. doi: 10.1186/s12891-020-03914-x.

DOI:10.1186/s12891-020-03914-x
PMID:33482782
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7825159/
Abstract

BACKGROUND

Chronic musculoskeletal pain (CMP) affects daily life function and is the most prevalent disorder in primary health care. The primary objective was to examine demographic factors and pain characteristics associated with reduced health-related quality of life (HRQoL) among patients in primary care reporting CMP. Our secondary objective was to compare HRQoL in patients with and without CMP.

METHOD

This cross-sectional study was conducted in Trondheim, Norway. Twenty randomly selected GPs, and their listed patients aged 21-58 were invited to participate. Self-reported CMP data was collected using online questionnaires. HRQoL was measured by the 15D questionnaire, total score of 0.9 was used as cut-off for clinical reduced HRQoL.

RESULTS

A total of 969 patients (650 females) were recruited from six GPs' patient lists, mean age 45.6 (SD 10.1). CMP was reported by 517 (53%). Factors significantly associated with reduced HRQoL were gender (OR 2.0, 95% CI 1.2, 3.4), disability pension (OR 26.6, 95% CI 3.1, 228.0), mood (OR 1.3, 95% CI 1.1, 1.6), relations with other people (OR 0.8, 95% CI 0.6, 0.9), sleep (OR 1.2, 95% CI 1.0, 1.3) and enjoyment (OR 1.2, 95% CI 1.0). CMP patients had significantly lower total HRQoL score compared to patients without CMP (Between group difference 0.08, 95% CI 0.07-0.09). Half of the CMP patients reported a HRQoL score < 0.9 compared to 14% in the no CMP group.

CONCLUSIONS

Being female, receiving disability pension, and several psychosocial factors were found highly associated with reduced HRQoL in CMP patients, whereas pain characteristics were not. Patients with CMP reported statistically and clinically significant lower HRQoL than patients without CMP. Due to low response rate the conclusions must be handled with caution.

TRIAL REGISTRATION

Clinicaltrials.gov (NCT02020772).

摘要

背景

慢性肌肉骨骼疼痛(CMP)会影响日常生活功能,是初级保健中最常见的疾病。主要目的是研究与初级保健中报告 CMP 的患者健康相关生活质量(HRQoL)降低相关的人口统计学因素和疼痛特征。我们的次要目的是比较 CMP 患者和无 CMP 患者的 HRQoL。

方法

这是一项在挪威特隆赫姆进行的横断面研究。随机选择了 20 名全科医生及其列出的 21-58 岁患者参加。使用在线问卷收集自我报告的 CMP 数据。HRQoL 通过 15D 问卷进行测量,总分为 0.9 用作临床 HRQoL 降低的截止值。

结果

从六名全科医生的患者名单中招募了 969 名患者(650 名女性),平均年龄为 45.6(SD 10.1)。517 名(53%)患者报告有 CMP。与降低的 HRQoL 显著相关的因素包括性别(OR 2.0,95% CI 1.2,3.4)、残疾抚恤金(OR 26.6,95% CI 3.1,228.0)、情绪(OR 1.3,95% CI 1.1,1.6)、与他人的关系(OR 0.8,95% CI 0.6,0.9)、睡眠(OR 1.2,95% CI 1.0,1.3)和享受(OR 1.2,95% CI 1.0)。与无 CMP 患者相比,CMP 患者的总 HRQoL 评分明显较低(组间差异 0.08,95% CI 0.07-0.09)。一半的 CMP 患者报告 HRQoL 评分 < 0.9,而无 CMP 组为 14%。

结论

女性、领取残疾抚恤金以及一些社会心理因素与 CMP 患者的 HRQoL 降低高度相关,而疼痛特征则没有。与无 CMP 患者相比,CMP 患者报告的 HRQoL 统计学和临床意义上均显著降低。由于低应答率,必须谨慎解释结论。

试验注册

Clinicaltrials.gov(NCT02020772)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b65e/7825159/b0a68160fb2b/12891_2020_3914_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b65e/7825159/0c2efc83bd4c/12891_2020_3914_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b65e/7825159/b0a68160fb2b/12891_2020_3914_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b65e/7825159/0c2efc83bd4c/12891_2020_3914_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b65e/7825159/b0a68160fb2b/12891_2020_3914_Fig2_HTML.jpg

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