Bograd Alexandra, Himmel Isabelle, Pfister Isabel B, Seiler Theo G, Frueh Beatrice E, Tappeiner Christoph
Department of Ophthalmology, Bern University Hospital, Inselspital, University of Bern, Bern, Switzerland.
Berner Augenklinik, Bern, Switzerland.
Graefes Arch Clin Exp Ophthalmol. 2024 Mar;262(3):891-901. doi: 10.1007/s00417-023-06219-6. Epub 2023 Sep 9.
To assess the feasibility and reliability of biometric measurements taken with the Eyestar 900 device in keratoconus eyes in comparison with those taken with the Pentacam HR and IOLMaster 700.
Seventy-five eyes of 75 patients with keratoconus were included. The central corneal thickness (CCT), thinnest point of corneal thickness (TCT), axial length (AL), flat (K1) and steep (K2) anterior and posterior (Kp1, Kp2) keratometry, maximal keratometry (KMax) and anterior chamber depth (ACD) were compared between the Eyestar 900, Pentacam HR and IOLMaster 700. Reliability parameters such as the coefficient of variation (CoV) and intraclass correlation coefficient (ICC) were calculated. Pearson's r was determined to assess the correlation between devices.
A high repeatability (CoV < 1%) and intraclass correlation (ICC > 0.9) was found for all devices, led by AL, TCT, K1 and K2 (CoV 0.01-0.36%; ICC 0.994-1.00). The largest correlation between devices was found for AL (Eyestar vs. IOLMaster, r = 1.0), K1 (Eyestar vs. IOLMaster, r = 0.997) and ACD (Eyestar vs. IOLMaster, r = 0.995; Pentacam vs. IOLMaster, r = 0.987; Eyestar vs. Pentacam, r = 0.983), but there were significant differences in measured values between devices (p < 0.001), whereas the correlation was only slightly lower (r = 0.947 to 0.994) for KMax, CCT, TCT, K2, Kp1 and Kp2.
Keratometric and axial length measurements with the Eyestar 900 were feasible and revealed a high repeatability and a good correlation to the other devices in eyes with keratoconus.
与Pentacam HR和IOLMaster 700相比，评估使用Eyestar 900设备对圆锥角膜眼进行生物测量的可行性和可靠性。
纳入75例圆锥角膜患者的75只眼。比较Eyestar 900、Pentacam HR和IOLMaster 700之间的中央角膜厚度（CCT）、角膜厚度最薄点（TCT）、眼轴长度（AL）、平坦（K1）和陡峭（K2）的前后角膜曲率（Kp1、Kp2）、最大角膜曲率（KMax）和前房深度（ACD）。计算变异系数（CoV）和组内相关系数（ICC）等可靠性参数。确定Pearson相关系数r以评估设备之间的相关性。
所有设备均具有高重复性（CoV < 1%）和组内相关性（ICC > 0.9），其中以AL、TCT、K1和K2最为突出（CoV 0.01 - 0.36%；ICC 0.994 - 1.00）。设备之间相关性最大的是AL（Eyestar与IOLMaster，r = 1.0）、K1（Eyestar与IOLMaster，r = 0.997）和ACD（Eyestar与IOLMaster，r = 0.995；Pentacam与IOLMaster，r = 0.987；Eyestar与Pentacam，r = 0.983），但设备之间的测量值存在显著差异（p < 0.001），而对于KMax、CCT、TCT、K2、Kp1和Kp2，相关性仅略低（r = 0.947至0.994）。
使用Eyestar 900进行角膜曲率和眼轴长度测量是可行的，并且在圆锥角膜眼中显示出高重复性以及与其他设备的良好相关性。
