Suppr超能文献

binge 饮酒与缺血性心脏病和中风风险的关联: pooled 挪威健康调查研究。

Associations of Binge Drinking With the Risks of Ischemic Heart Disease and Stroke: A Study of Pooled Norwegian Health Surveys.

出版信息

Am J Epidemiol. 2021 Aug 1;190(8):1592-1603. doi: 10.1093/aje/kwab063.

Abstract

Norwegian health survey data (1987-2003) were analyzed to determine if binge drinking increases the risk of incident major events from ischemic heart disease (IHD) and stroke. Among current drinkers reporting average alcohol intakes of 2.00-59.99 g/day (n = 44,476), frequent binge drinking (≥5 units at least once per month) was not associated with a greater risk of IHD (adjusted hazard ratio (HR) = 0.91, 95% confidence interval (CI): 0.76, 1.09) or stroke (adjusted HR = 0.98, 95% CI: 0.81, 1.19), in comparison with participants who reported that they never or only infrequently (less than once per month) had episodes of binge drinking. Participants with an average alcohol intake of 2.00-59.99 g/day had a lower risk of IHD in comparison with participants with very low intakes (<2.00 g/day), both among frequent binge drinkers (adjusted HR = 0.67, 95% CI: 0.56, 0.80) and among never/infrequent binge drinkers (adjusted HR = 0.75, 95% CI: 0.67, 0.84). The findings suggest that frequent binge drinking, independent of average alcohol intake, does not increase the risk of incident IHD or stroke events. However, the findings should be interpreted in light of the limitations of the study design.

摘要

对挪威健康调查数据(1987-2003 年)进行分析,以确定 binge drinking 是否会增加缺血性心脏病(IHD)和中风的发病风险。在报告平均酒精摄入量为 2.00-59.99 g/天的当前饮酒者中(n=44476),频繁 binge drinking(每月至少一次饮酒 5 个单位以上)与 IHD(调整后的危险比(HR)=0.91,95%置信区间(CI):0.76,1.09)或中风(调整后的 HR=0.98,95%CI:0.81,1.19)的发病风险增加无关,与报告从不或很少(每月少于一次) binge drinking 的参与者相比。与低摄入量(<2.00 g/天)的参与者相比,每日酒精摄入量为 2.00-59.99 g 的参与者的 IHD 发病风险较低,在频繁 binge drinkers(调整后的 HR=0.67,95%CI:0.56,0.80)和从不/很少 binge drinkers(调整后的 HR=0.75,95%CI:0.67,0.84)中均如此。这些发现表明,频繁 binge drinking 独立于平均酒精摄入量,不会增加 IHD 或中风事件的发病风险。然而,应该根据研究设计的局限性来解释这些发现。

相似文献

6
Increased stroke risk is related to a binge-drinking habit.中风风险增加与暴饮习惯有关。
Stroke. 2008 Dec;39(12):3179-84. doi: 10.1161/STROKEAHA.108.520817. Epub 2008 Oct 2.

引用本文的文献

2
Alcohol and Cardiovascular Disease: Helpful or Hurtful.酒精与心血管疾病:有益还是有害
Rev Cardiovasc Med. 2023 Apr 19;24(4):121. doi: 10.31083/j.rcm2404121. eCollection 2023 Apr.

本文引用的文献

1
Alcohol Consumption and Cardiovascular Disease: A Mendelian Randomization Study.饮酒与心血管疾病:一项孟德尔随机化研究。
Circ Genom Precis Med. 2020 Jun;13(3):e002814. doi: 10.1161/CIRCGEN.119.002814. Epub 2020 May 5.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验