Ozturk Tuncer, Sengul Demet, Sengul Ilker
Department of General Surgery, Giresun University Faculty of Medicine, TR28100 Giresun, Turkey.
Department of Pathology, Giresun University Faculty of Medicine, TR28100 Giresun, Turkey.
Ann Afr Med. 2021 Jan-Mar;20(1):1-8. doi: 10.4103/aam.aam_69_19.
Helicobacter pylori (H. pylori) is a Gram-negative, helically shaped flagellated bacterium. Major diseases associated with H. pylori infection include peptic ulcer, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. The incidence of H. pylori in the anatomotopographic regions of the stomach, such as antrum, corpus, fundus, and incisura angularis, has been investigated. Do the rates of H. pylori in the settlements change over time according to the age ranges of the hosts? Does this change affect the diseases caused by or related to H. pylori? It is estimated that the outcomes, which have been obtained, may provide a new perspective in terms of understanding the etiopathogenesis of H. pylori-induced diseases. A comprehensive literature search of PubMed/MEDLINE databases had been conducted using a combination of terms, "Helicobacter pylori," "Sydney System," "stomach," "pyloric antrum," "gastric corpus," "stomach cancer," and "Helicobacter pylori and age." There are very few articles examining the relationship between the topographic locations of H. pylori and host age range in the English language literature. Therefore, it is also purposed to emphasize the outcomes of our current research about the mentioned topic. In our opinion, similar studies should reveal the settlement and age range in the different geographic locations and societies as in our study. We believe that these findings will contribute to the efforts for understanding overtly of H. pylori-induced disease of the stomach.
幽门螺杆菌（H. pylori）是一种革兰氏阴性、螺旋状、有鞭毛的细菌。与幽门螺杆菌感染相关的主要疾病包括消化性溃疡、胃腺癌和黏膜相关淋巴组织淋巴瘤。人们已经对幽门螺杆菌在胃的解剖部位（如胃窦、胃体、胃底和胃角切迹）的发生率进行了研究。幽门螺杆菌在不同人群中的感染率是否会随着宿主年龄范围的变化而随时间改变？这种变化是否会影响由幽门螺杆菌引起或与之相关的疾病？据估计，已获得的研究结果可能会为理解幽门螺杆菌所致疾病的病因发病机制提供一个新的视角。我们使用“幽门螺杆菌”“悉尼系统”“胃”“幽门窦”“胃体”“胃癌”和“幽门螺杆菌与年龄”等术语组合，对PubMed/MEDLINE数据库进行了全面的文献检索。在英语文献中，很少有文章研究幽门螺杆菌的地形位置与宿主年龄范围之间的关系。因此，本文的目的还在于强调我们当前关于上述主题的研究结果。我们认为，类似的研究应像我们的研究一样，揭示不同地理位置和社会中的幽门螺杆菌分布情况和年龄范围。我们相信，这些发现将有助于更深入地理解幽门螺杆菌引起的胃部疾病。
