Dipartimento di Chimica e Tecnologie del Farmaco, Università degli Studi di Roma "La Sapienza", Piazzale Aldo Moro 5, 00185 Roma, Italy.
Dipartimento di Biologia Ambientale, Università degli Studi di Roma "La Sapienza", P.le Aldo Moro 5, 00185 Rome, Italy.
Molecules. 2021 Mar 19;26(6):1731. doi: 10.3390/molecules26061731.
Strawberries, belonging to cultivar Clery ( × Duchesne ex Weston) and to a graft obtained by crossing Clery and L., were chosen for a study on their health potential, with regard to the prevention of chronic and degenerative diseases. Selected samples, coming from fresh and defrosted berries, submitted to different homogenization techniques combined with thermal and microwave treatments, had been previously analyzed in their polyphenolic content and antioxidant capacity. In the present work, these homogenates were evaluated in relation to their enzymatic inhibition activity towards acetylcholinesterase and butyrylcholinesterase, α-amylase, α-glucosidase and tyrosinase. All these enzymes, involved in the onset of diabetes, and neurodegenerative and other chronic diseases, were modulated by the tested samples. The inhibitory effect on tyrosinase and cholinesterase was the most valuable. Antifungal activity against , recently shown to play a crucial role in human gut diseases as well as diabetes, rheumatoid arthritis and Alzheimer's disease, was also shown in vitro and confirmed by the in vivo text on . Overall, the obtained results confirm once again the health potential of strawberries; however, the efficacy is dependent on high quality products submitted to correct processing flow charts.
草莓，属于品种 Clery（×Duchesne ex Weston）和 Clery 与 L. 杂交获得的接穗，因其预防慢性和退行性疾病的潜力而被选择进行研究。从新鲜和解冻的浆果中选择的样本，经过不同的均化技术与热和微波处理相结合，已经在其多酚含量和抗氧化能力方面进行了分析。在本工作中，这些匀浆与它们对乙酰胆碱酯酶和丁酰胆碱酯酶、α-淀粉酶、α-葡萄糖苷酶和酪氨酸酶的酶抑制活性有关。所有这些参与糖尿病、神经退行性疾病和其他慢性疾病的发生的酶，都被测试样本所调节。对酪氨酸酶和胆碱酯酶的抑制作用最为显著。体外实验还显示了草莓对 的抗真菌活性，最近的研究表明，它在人类肠道疾病以及糖尿病、类风湿关节炎和阿尔茨海默病中起着至关重要的作用，体内实验也证实了这一点。总的来说，所得结果再次证实了草莓的健康潜力；然而，功效取决于高质量的产品，并经过正确的加工流程图。
