The impact of first and second wave of the COVID-19 pandemic in society: comparative analysis to support control measures to cope with negative effects of future infectious diseases.

The goal of this study is a comparative analysis of the first and second wave of the Coronavirus disease 2019 (COVID-19) to assess the impact on health of people for designing effective policy responses to constrain negative effects of future pandemic waves of COVID-19 and similar infectious diseases in society. The research here focuses on a case study of Italy, one of the first countries to experience a rapid increase in numbers of COVID-19 related infected individuals and deaths. Statistical analyses, based on daily data from February 2020 to February 2021, suggest that the first wave of COVID-19 pandemic in Italy had a high negative impact on health of people over February-May 2020 period; after that, negative effects declined from June 2020 onwards. Second wave of COVID-19 pandemic from August 2020 to February 2021 had a growing incidence of confirmed cases also associated with variants of coronavirus, whereas admissions to Intensive Care Units and total deaths had lower levels compared to first wave of COVID-19. Lessons learned of this comparative analysis between first and second wave of the COVID-19 pandemic in Italy can be generalized in similar geo-economic areas to support effective policy responses of crisis management to constrain the negative impact on health of people of recurring waves of COVID-19 pandemic and similar infectious diseases in future.