Kocaer Ahmet, Sarpel Tunay, Gökçen Neslihan, Başaran Sibel, Coşkun Benlidayı İlke
Department of Physical Medicine and Rehabilitation, Çukurova University Faculty of Medicine, Adana, Turkey.
Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Çukurova University Faculty of Medicine, Adana, Turkey.
Turk J Phys Med Rehabil. 2021 Mar 4;67(1):84-90. doi: 10.5606/tftrd.2021.5323. eCollection 2021 Mar.
This study aims to evaluate the association of serum vitamin D level with proximal muscle strength, tone, elasticity, and stiffness in elderly.
Between September 2017 and January 2018, a total of 109 participants (21 males, 88 females; mean age: 71.2±4.6 years; range, 65 to 85 years) were included in the study. The proximal muscle strength was evaluated by MicroFET® 3 device. The muscle tone, elasticity, and stiffness were measured using the MyotonPRO® digital palpation device. Serum 25-hydroxyvitamin D [25(OH)D] level was tested by high-performance liquid chromatography. A receiver operating characteristic (ROC) curve was performed to evaluate the potential role of MicroFET® 3-measured proximal muscle strength in the quantification of vitamin D status.
Vitamin D sufficient participants had a higher proximal muscle strength (p<0.001). Quadriceps and hamstring elasticity at the non-dominant site were significantly higher in vitamin D sufficient group (p<0.05). The ROC analysis indicated that the deltoid muscle strength had the potential of determining vitamin D insufficiency with moderate accuracy (area under the curve=0.744; 95% confidence interval: 0.643-0.845; p<0.001).
Proximal muscle strength, elasticity, and physical performance are associated with vitamin D status. Proximal muscle strength measured by a hand-held dynamometer can be used as a predictor of hypovitaminosis D in elderly.
本研究旨在评估老年人群血清维生素D水平与近端肌肉力量、张力、弹性和僵硬度之间的关联。
2017年9月至2018年1月期间，共有109名参与者（21名男性，88名女性；平均年龄：71.2±4.6岁；范围为65至85岁）纳入本研究。使用MicroFET® 3设备评估近端肌肉力量。使用MyotonPRO®数字触诊设备测量肌肉张力、弹性和僵硬度。采用高效液相色谱法检测血清25-羟基维生素D [25(OH)D]水平。绘制受试者工作特征（ROC）曲线，以评估MicroFET® 3测量的近端肌肉力量在量化维生素D状态中的潜在作用。
维生素D充足的参与者近端肌肉力量更高（p<0.001）。维生素D充足组非优势侧股四头肌和腘绳肌的弹性显著更高（p<0.05）。ROC分析表明，三角肌力量有潜力以中等准确度确定维生素D不足（曲线下面积=0.744；95%置信区间：0.643 - 0.845；p<0.001）。
近端肌肉力量、弹性和身体机能与维生素D状态相关。手持式测力计测量的近端肌肉力量可作为老年人维生素D缺乏症的预测指标。
