Gianfreda Francesco, Antonacci Donato, Raffone Carlo, Muzzi Maurizio, Pistilli Valeria, Bollero Patrizio
Department of Industrial Engineering, University of Rome "Tor Vergata", 00133 Rome, Italy.
Independent Researcher, 70121 Bari, Italy.
Materials (Basel). 2021 May 17;14(10):2608. doi: 10.3390/ma14102608.
The surface topography of dental implants plays an important role in cell-surface interaction promoting cell adhesion, proliferation and differentiation influencing osseointegration. A hydrophilic implant leads to the absorption of water molecules and subsequently promotes the adhesion of cells to the implant binding protein. Dried salts on the implant surfaces allow one to store the implant surfaces in a dry environment while preserving their hydrophilic characteristics. This process has been identified as "dry technology". The aim of the present study is to describe from a micrometric and nanometric point of view the characteristics of this new bioactivated surface obtained using salts dried on the surface. Topographic analysis, energy-dispersive X-ray spectroscopy, and contact angle characterization were performed on the samples of a sandblasted and dual acid-etched surface (ABT), a nanosurface (Nano) deriving from the former but with the adding of salts air dried and a nanosurface with salts dissolved with distilled water (Nano HO). The analysis revealed promising results for nanostructured surfaces with increased wettability and a more articulated surface nanotopography than the traditional ABT surface. In conclusion, this study validates a new promising ultra-hydrophilic nano surface obtained by sandblasting, double acid etching and surface salt deposition using dry technology.
牙种植体的表面形貌在促进细胞黏附、增殖和分化的细胞-表面相互作用中发挥着重要作用，进而影响骨结合。亲水性种植体能够吸附水分子，随后促进细胞与种植体结合蛋白的黏附。种植体表面的干燥盐类能够在保持其亲水性的同时，使种植体表面在干燥环境中储存。这一过程被确定为“干燥技术”。本研究的目的是从微米和纳米角度描述通过表面干燥盐类获得的这种新型生物活性表面的特征。对喷砂和双重酸蚀表面（ABT）、由前者衍生但添加了风干盐类的纳米表面（Nano）以及盐类用蒸馏水溶解的纳米表面（Nano HO）的样本进行了形貌分析、能量色散X射线光谱分析和接触角表征。分析结果显示，与传统ABT表面相比，纳米结构表面具有更好的润湿性和更复杂的表面纳米形貌，结果令人满意。总之，本研究验证了一种通过喷砂、双重酸蚀和使用干燥技术进行表面盐沉积获得的新型超亲水性纳米表面。
