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盐生植物生物活性提取物在抗炎、止痛和抗生素类机制方面的药理学研究进展。

Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms.

机构信息

Department of Health Science and Technology, Aalborg University, 9220 Aalborg, Denmark.

Department of Energy Technology, Aalborg University, 9220 Aalborg, Denmark.

出版信息

Molecules. 2021 May 24;26(11):3140. doi: 10.3390/molecules26113140.

Abstract

The pharmacological activities in bioactive plant extracts play an increasing role in sustainable resources for valorization and biomedical applications. Bioactive phytochemicals, including natural compounds, secondary metabolites and their derivatives, have attracted significant attention for use in both medicinal products and cosmetic products. Our review highlights the pharmacological mode-of-action and current biomedical applications of key bioactive compounds applied as anti-inflammatory, bactericidal with antibiotics effects, and pain relief purposes in controlled clinical studies or preclinical studies. In this systematic review, the availability of bioactive compounds from several salt-tolerant plant species, mainly focusing on the three promising species , and , are summarized and discussed. All three of them have been widely used in natural folk medicines and are now in the focus for future nutraceutical and pharmacological applications.

摘要

生物活性植物提取物中的药理学活性在可持续资源的增值和生物医学应用中发挥着越来越重要的作用。生物活性植物化学成分,包括天然化合物、次生代谢物及其衍生物,已引起人们的广泛关注,可用于药品和化妆品。我们的综述重点介绍了关键生物活性化合物在抗炎、杀菌(具有抗生素作用)和缓解疼痛方面的药理学作用模式和当前的生物医学应用,这些化合物在对照临床试验或临床前研究中得到了应用。在本系统综述中,总结和讨论了几种耐盐植物物种的生物活性化合物的可用性,主要集中在三个有前途的物种、和 上。这三种植物在天然民间药物中被广泛应用,现在是未来营养和药理学应用的重点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8e2/8197292/37f75755dc42/molecules-26-03140-g001.jpg

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