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巴西阿拉戈斯州出现的 COVID-19 新型 SARS-CoV-2(P1/Gamma)变异株。

New Brazilian variant of the SARS-CoV-2 (P1/Gamma) of COVID-19 in Alagoas state.

机构信息

Centro Universitário CESMAC, Maceió, Alagoas, Brasil; Laboratório de Neurociência e comportamento, Núcleo de Ciências Biológicas, Universidade Estadual de Ciências da Saúde de Alagoas (NUCIB-UNCISAL), Maceió, AL, Brasil; Departamento de Neurologia e Neurocirurgia, Universidade Federal de São Paulo (EPM/UNIFESP), Escola Paulista de Medicina, São Paulo, SP, Brasil.

Centro Universitário CESMAC, Maceió, Alagoas, Brasil; Universidade Federal de Alagoas (HUPAA/UFAL/EBSERH), Divisão de apoio e diagnóstico terapêutico do Hospital Universitário, Maceió, AL, Brasil.

出版信息

Braz J Infect Dis. 2021 May-Jun;25(3):101588. doi: 10.1016/j.bjid.2021.101588. Epub 2021 May 19.

Abstract

Since the beginning of 2020, health authorities have been monitoring the cases of Coronavirus Disease 2019 (COVID-19), which has grown every day in Brazil and around the world, becoming pandemic. The new coronavirus, also called SARS-CoV-2 by scientists spreads rapidly, causing fear, deaths, and threats for the economy of several countries. This work aimed to describe the clinical characterization of the first cases of a new Brazilian variant of SARS-CoV-2 (P1) in the State of Alagoas, which occurred on February 16th, 2021. Two cases are described: first, a person infected in Amazonas State, where the new variant P1 was first described, who migrated to Alagoas State, and second, a case of probable community transmission within Alagoas, since the patient had no history of recent travel. In both confirmed cases the symptoms were mild. Further studies are necessary to better understand the clinical behavior of P1 SARS-CoV-2 variant and also the associated sequelae in the context of COVID-19.

摘要

自 2020 年初以来,卫生当局一直在监测 2019 年冠状病毒病(COVID-19)的病例,巴西和世界各地的病例每天都在增加,已成为大流行。这种新型冠状病毒也被科学家称为 SARS-CoV-2,传播迅速,引起了几个国家的恐惧、死亡和经济威胁。这项工作旨在描述 2021 年 2 月 16 日在阿拉戈斯州首次出现的新型 SARS-CoV-2(P1)巴西变异株的首例病例的临床特征。描述了两种情况:首先,是在新变异株 P1 首次描述的亚马孙州感染的人,他迁移到了阿拉戈斯州;其次,是在阿拉戈斯州发生的一起可能的社区传播病例,因为患者没有近期旅行史。在这两个确诊病例中,症状均较轻。需要进一步研究以更好地了解 P1 SARS-CoV-2 变异株的临床行为以及 COVID-19 背景下的相关后遗症。

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