Leong Russell, Lee Tin-Suet Joan, Chen Zejia, Zhang Chelsea, Xu Jianping
Faculty of Health Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada.
Department of Biology and Institute of Infectious Diseases Research, McMaster University, Hamilton, ON L8S 4K1, Canada.
Infect Dis Rep. 2021 Jun 21;13(2):582-596. doi: 10.3390/idr13020054.
Since the beginning of 2020, COVID-19 has been the biggest public health crisis in the world. To help develop appropriate public health measures and deploy corresponding resources, many governments have been actively tracking COVID-19 in real time within their jurisdictions. However, one of the key unresolved issues is whether COVID-19 was distributed differently among different age groups and between the two sexes in the ongoing pandemic. The objectives of this study were to use publicly available data to investigate the relative distributions of COVID-19 cases, hospitalizations, and deaths among age groups and between the sexes throughout 2020; and to analyze temporal changes in the relative frequencies of COVID-19 for each age group and each sex. Fifteen countries reported age group and/or sex data of patients with COVID-19. Our analyses revealed that different age groups and sexes were distributed differently in COVID-19 cases, hospitalizations, and deaths. However, there were differences among countries in both their age group and sex distributions. Though there was no consistent temporal change across all countries for any age group or either sex in COVID-19 cases, hospitalizations, and deaths, several countries showed statistically significant patterns. We discuss the potential mechanisms for these observations, the limitations of this study, and the implications of our results on the management of this ongoing pandemic.
自2020年初以来,新型冠状病毒肺炎(COVID-19)一直是全球最大的公共卫生危机。为了帮助制定适当的公共卫生措施并调配相应资源,许多政府一直在其辖区内积极实时追踪COVID-19。然而,一个关键的未解决问题是,在当前的疫情中,COVID-19在不同年龄组和两性之间的分布是否存在差异。本研究的目的是利用公开数据调查2020年全年COVID-19病例、住院病例和死亡病例在各年龄组以及两性之间的相对分布情况;并分析各年龄组和两性的COVID-19相对频率的时间变化。15个国家报告了COVID-19患者的年龄组和/或性别数据。我们的分析表明,不同年龄组和两性在COVID-19病例、住院病例和死亡病例中的分布存在差异。然而,各国在年龄组和性别分布方面都存在差异。尽管在所有国家中,任何年龄组或两性的COVID-19病例、住院病例和死亡病例都没有一致的时间变化,但有几个国家呈现出具有统计学意义的模式。我们讨论了这些观察结果的潜在机制、本研究的局限性以及我们的结果对当前这场疫情管理的影响。