Shi Qiang, Wang Guang-Yan, Cheng Yu-Hong, Pei Cheng
Department of Ophthalmology, the First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China.
Int J Ophthalmol. 2021 Jul 18;14(7):1013-1017. doi: 10.18240/ijo.2021.07.08. eCollection 2021.
To compare the differences and consistency of IOL-Master 700 biometers applying swept optical coherence tomography with the conventional IOL-Master 500 applying partial coherence interference in terms of the ocular biological parameters in adolescents with ametropia.
A total of 110 adolescents (110 eyes) with ametropia were collected, including 55 males and 55 females; age 10.69±2.81y. Ocular biological measurements were taken by IOL-Master 700 and IOL-Master 500 respectively to obtain biological parameters including axial length (AL), mean corneal anterior surface keratometry (K), anterior chamber depth (ACD), and horizontal corneal diameter (WTW). Paired -test was used to compare the differences between the two instruments. The intra-group correlation coefficient (ICC) and the Bland-Altman analysis were used to evaluate the consistency of parameter measurements between the two instruments for the four biological parameters.
Statistical analysis showed that there was no significant difference in the K value measured by IOL-Master 700 and IOL-Master 500 (=-1.644, =0.116). The average differences of the AL, ACD, and WTW distances between the two instruments are 0.028, 0.101 and 0.064 mm respectively, and the differences are statistically significant (=2.644, 12.505, 3.911, <0.001). The consistency study results indicated high correlation in the measurement of AL, K, ACD and WTW between the two instruments (ICC=0.994, 0.873, 0.927, 0.912).
The novel biometric instrument IOL-Master 700 makes no difference with IOL-Master 500 in the measurement of K. There are some differences in the values of AL, ACD, and WTW. However, the two instruments show good consistency in these four biological measurements. The measured values of K are interchangeable between the instruments. These two types of biometrics can be used as mutual reference in consideration of that the differences in AL, ACD, and WTW measurements are not sufficient to produce clinically meaningful differences.
比较采用扫频光学相干断层扫描技术的IOL-Master 700生物测量仪与采用部分相干干涉技术的传统IOL-Master 500生物测量仪在屈光不正青少年眼生物参数方面的差异和一致性。
收集110例屈光不正青少年（110只眼），其中男性55例，女性55例；年龄10.69±2.81岁。分别使用IOL-Master 700和IOL-Master 500进行眼生物测量，以获得包括眼轴长度（AL）、平均角膜前表面曲率（K）、前房深度（ACD）和水平角膜直径（WTW）在内的生物参数。采用配对t检验比较两种仪器之间的差异。采用组内相关系数（ICC）和Bland-Altman分析评估两种仪器对四个生物参数测量的一致性。
统计分析显示，IOL-Master 700和IOL-Master 500测量的K值无显著差异（t=-1.644，P=0.116）。两种仪器测量的AL、ACD和WTW距离的平均差异分别为0.028、0.101和0.064mm，差异具有统计学意义（t=2.644、12.505、3.911，P<0.001）。一致性研究结果表明，两种仪器在AL、K、ACD和WTW测量方面具有高度相关性（ICC=0.994、0.873、0.927、0.912）。
新型生物测量仪IOL-Master 700在K测量方面与IOL-Master 500无差异。AL、ACD和WTW值存在一些差异。然而，两种仪器在这四项生物测量中显示出良好的一致性。K的测量值在两种仪器之间可以互换。考虑到AL、ACD和WTW测量的差异不足以产生具有临床意义的差异，这两种生物测量方法可相互参考使用。
