Zhu Qianlong, Chen Xinjian, Meng Qingquan, Song Jiahuan, Luo Gaohui, Wang Meng, Shi Fei, Chen Zhongyue, Xiang Dehui, Pan Lingjiao, Li Zuoyong, Zhu Weifang
MIPAV Lab, School of Electronics and Information Engineering, Soochow University, Jiangsu 215006, China.
State Key Laboratory of Radiation Medicine and Protection, Soochow University, Jiangsu 215006, China.
Biomed Opt Express. 2021 Sep 24;12(10):6529-6544. doi: 10.1364/BOE.434841. eCollection 2021 Oct 1.
Accurate segmentation of optic disc (OD) and optic cup (OC) in fundus images is crucial for the analysis of many retinal diseases, such as the screening and diagnosis of glaucoma and atrophy segmentation. Due to domain shift between different datasets caused by different acquisition devices and modes and inadequate training caused by small sample dataset, the existing deep-learning-based OD and OC segmentation networks have poor generalization ability for different fundus image datasets. In this paper, adopting the mixed training strategy based on different datasets for the first time, we propose an encoder-decoder based general OD and OC segmentation network (named as GDCSeg-Net) with the newly designed multi-scale weight-shared attention (MSA) module and densely connected depthwise separable convolution (DSC) module, to effectively overcome these two problems. Experimental results show that our proposed GDCSeg-Net is competitive with other state-of-the-art methods on five different public fundus image datasets, including REFUGE, MESSIDOR, RIM-ONE-R3, Drishti-GS and IDRiD.
眼底图像中视盘(OD)和视杯(OC)的准确分割对于许多视网膜疾病的分析至关重要,例如青光眼的筛查和诊断以及萎缩分割。由于不同采集设备和模式导致不同数据集之间存在域偏移,以及小样本数据集导致训练不足,现有的基于深度学习的OD和OC分割网络对不同眼底图像数据集的泛化能力较差。在本文中,我们首次采用基于不同数据集的混合训练策略,提出了一种基于编码器 - 解码器的通用OD和OC分割网络(命名为GDCSeg - Net),该网络具有新设计的多尺度权重共享注意力(MSA)模块和密集连接深度可分离卷积(DSC)模块,以有效克服这两个问题。实验结果表明,我们提出的GDCSeg - Net在包括REFUGE、MESSIDOR、RIM - ONE - R3、Drishti - GS和IDRiD在内的五个不同公共眼底图像数据集上与其他现有先进方法具有竞争力。