Hashemi Behnam, Akram Firouzi-Amandi, Amirazad Halimeh, Dadashpour Mehdi, Sheervalilou Milad, Nasrabadi Davood, Ahmadi Majid, Sheervalilou Roghayeh, Ameri Shah Reza Mahdieh, Ghazi Farhood, Roshangar Leila
Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Immunology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
J Drug Deliv Sci Technol. 2022 Jan;67:102967. doi: 10.1016/j.jddst.2021.102967. Epub 2021 Nov 6.
The ongoing outbreak of the newly emerged coronavirus disease 2019, which has tremendously concerned global health safety, is the result of infection with severe acute respiratory syndrome of coronavirus 2 with high morbidity and mortality. Because of the coronavirus has no specific treatment, so it is necessary to early detection and produce antiviral agents and efficacious vaccines in order to prevent the contagion of coronavirus. Due to the unique properties of nanomaterials, nanotechnology appears to be a highly relevant discipline in this global emergency, providing expansive chemical functionalization to develop advanced biomedical tools. Fascinatingly, nanomedicine as a hopeful approach for the treatment and diagnosis of diseases, could efficiently help success the fight among coronavirus and host cells. In this review, we will critically discuss how nanomedicine can play an indispensable role in creating useful treatments and diagnostics for coronavirus.
新出现的2019冠状病毒病的持续爆发极大地关乎全球卫生安全,它是由严重急性呼吸综合征冠状病毒2感染所致,具有高发病率和高死亡率。由于冠状病毒没有特效治疗方法,因此有必要尽早检测并研发抗病毒药物和有效的疫苗,以防止冠状病毒传播。由于纳米材料具有独特性质,纳米技术在这一全球紧急情况中似乎是一个高度相关的学科,可提供广泛的化学功能化以开发先进的生物医学工具。令人着迷的是,纳米医学作为一种治疗和诊断疾病的有前景的方法,可以有效地助力抗击冠状病毒与宿主细胞之间的斗争。在本综述中,我们将批判性地讨论纳米医学如何在为冠状病毒创造有用的治疗方法和诊断手段方面发挥不可或缺的作用。